Morfološko-anatomske, radiološke i kliničke značajke tipa 6 deformacije nosnog septuma u čovjeka

master's thesis

• Title (english): Morphologic-anatomical, radiological and clinical features of the type 6 of nasal septum deformities in man
• Author: Borna Arsov
• Mentor: Mario Bilić (mentor)
• Committee member: Srećko Branica (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Mario Bilić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

Uvod: Svrha ovoga istraživanja je bila utvrditi postoje li podudarnosti između
učestalosti, anatomsko-morfoloških, radioloških i kliničkih znakova karakterističnih za
tip 6 deformacija nosnog septuma. ----- Metode i materijali: Makroskopski je pregledano
je 114 nasumice odabranih maceriranih ljudskih lubanja (>18 godina; 75 muški, 28
žene). Potom su sve navedene lubanje pregledane i radiološki i to snimanjem
kompjuterskom tomografijom. Sve su lubanje bile skenirane u fiksnoj poziciji koristeći
„cone beam“ kompjuteriziranu tomografiju (CBCT) na aparatu SCANORA® 3D;
SOREDEX (Finska); snimke su rađene u digitalnim slikama i pomoću obrazaca
medicinskog formata. Klinička je incidencija ovoga tipa deformacija nosnog septuma
promatrana i retrogradno, odnosno iz literaturnih podataka koji potječu iz studija
rađenih u raznim dijelovima svijeta. ----- Rezultati: Učestalost tipa 6 je u bolesnika
varirala između 9-11% dok je ona na CT snimkama lubanja bila 7.9%. Makroskopski
je utvrđena učestalost koja je bila dva do tri puta veća od prethodnih dviju (21.1%).
----- Zaključci: Tip 6 deformacija nosnog septuma se može uspješno prepoznati bilo
kliničkim pregledom (prednja rinoskopija), bilo na koronalnim snimkama
kompjuteriztirane tomografije. Promatranje na maceriranim ljudskim lubanjama pruža
znatno lakši pristup morfologiji ovoga područja te daje uvid u statistički značajnu,
veću učestalost. Tip 6 zbog njegove genske pozadine i povezanosti s nasljednim
bolestima i stanjima kao što su rascjep usne i/ili nepca i akutni koronarni sindrom
treba posebno pratiti i registrirati.

Abstract (english)

Introduction: The aim of this study was to examine the possible correspondence
between the incidence of the anatomic-morphologic, radiologic and clinical signs
characteristic for the type 6 of the nasal septal deformities. ----- Methods and materials:
An amount of 114 randomly selected macerated human skulls (>18 years, 75 males,
28 females) have been examined by means of macroscopic inspection. All the skulls
have been also examined by means of CT scanning in coronal projection in a fixed
position using the " cone beam " computed tomography (CBCT) at SCANORA® 3D;
SOREDEX. Clinical incidence of this type has been studied using the literature data
from various studies. ----- Results: The incidence of the type 6 in patients ranged
between 9-11% while the incidence found on CT scans of the macerated skulls was
7.9%. However, the incidence found by macroscopic observations of the macerated
skulls was bigger (21.1%). ----- Conclusions: Type 6 nasal septal deformity can be
successfully recognized both during the clinical examination (anterior rhinoscopy)
and on the coronal CT-scans. The observations on the macerated human skulls offer
much easier approach and shows a statistically significant higher incidence. Type 6
deserves particular attention because of its direct connection to the inherited
diseases like cleft lip/palate and acute coronary syndrome.

• Keywords: deformacije nosnog septuma; tip 6; kompjutorska tomografija; macerirane lubanje; učestalost
• Keywords (english): nasal septal deformities; type 6; computed tomography; macerated skulls; incidence
• Language: croatian
• URN:NBN: urn:nbn:hr:105:579629
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-01-08 14:50:16