Transcatheter aortic valve implantation

master's thesis

• Author: Jamal Ahel
• Mentor: Boris Starčević (mentor)
• Committee member: Boris Starčević (predsjednik povjerenstva)
• Committee member: Joško Bulum (član povjerenstva)
• Committee member: Boško Skorić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2015-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery

Abstract

Aortic stenosis is the most common valvular heart disease, with it’s incidence growing in developed countries, as the population ages. When it becomes symptomatic it tends to take a rapidly progressive course and soon requires intervention in the form of aortic valve replacement. If left untreated, mortality rates are as high as 50% within 2 years of symptom onset. Surgical
replacement of the aortic valve can significantly increase survival in such patients and reduce symptoms of the disease. Unfortunately, the existence of many comorbidities are often found in such patients and may severely influence the operative risk and outcome of the aortic valve replacement surgical procedure, thence many patients are doomed inoperable and unfit for
surgery. This category of inoperable patients comprises up to 30% of cases of severe symptomatic AS. Up until 2002, this group of patients did not have a viable alternative treatment. In 2002, however, the first transcatheter aortic valve implantation procedure was performed where the valve was introduced to the appropriate position by means of a catheter. Transcatheter aortic valve implantation is now the treatment of choice for high risk and inoperable patients with severe symptomatic aortic stenosis. Despite increasing advantages of transcatheter aortic valve implantation, however, several important setbacks and complications still exist and many improvements to the procedure are possible and necessary.

• Keywords: Transcatheter Aortic Valve Implantation; Aortic Valve Stenosis; Heart Team
• Language: english
• URN:NBN: urn:nbn:hr:105:152194
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-12-09 13:03:17