Usporedba rezultata stapedotomije korištenjem triju različitih proteza

master's thesis

• Title (english): Comparison of hearing outcomes after stapes surgery depending on prosthesis type
• Author: Lucija Dobrić
• Mentor: Andro Košec (mentor)
• Committee member: Jakov Ajduk (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Andro Košec (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract

Otoskleroza je bolest koju karakterizira patološki proces pregradnje kosti u kojem se normalna, gusta endohondralna kost zamjenjuje metaplastičnom spongiozom, u koju se taloži kalcij. Novoformirana nepravilna i kruta kost fiksira pločicu stremena u ovalnom prozoru, što dovodi do provodnog gubitka sluha. Najučinkovitije liječenje otoskleroze je kirurško - stapedektomija ili stapedotomija. Stapedektomija uključuje potpuno uklanjanje stremena, nakon čega slijedi postavljanje proteze i transplantata mekog tkiva. S druge strane, stapedotomija uključuje stvaranje otvora u pločici stremena, u koji se zatim stavlja proteza. U stapedotomiji se koristi niz različitih proteza, no ovaj pregledni rad u fokus stavlja Nitinol protezu, Causse Loop Piston protezu i Big Easy Piston protezu, uspoređujući njihovu djelotvornost u postoperativnom poboljšanju praga sluha. Osnovna mjera poboljšanja sluha je zatvaranje zračno-koštanog prozora (eng. air-bone gap, ABG), izračunat kao razlika preoperativnog i postoperativnog ABG-a. Na osnovu tih vrijednosti je zaključeno da nema značajne razlike u postoperativnim ishodima sluha među tri uspoređivana tipa proteza. Vrsta kirurškog pristupa i tip proteze moraju biti odabrani u skladu s individualnim karakteristikama pacijenta.

Abstract (english)

Otosclerosis is a disease characterized by a pathological bone remodeling process in which normal, dense endochondral bone is replaced by metaplastic spongiosa, in which calcium is deposited. The newly formed irregular and rigid bone fixes the stapes plate in the oval window, resulting in conductive hearing loss. The most effective treatment for otosclerosis is surgical – stapedectomy or stapedotomy. Stapedectomy involves the complete removal of the stapes, followed by the placement of a prosthesis and soft tissue graft. On the other hand, stapedotomy involves creating a small hole in the stapes plate, into which a prosthesis is then inserted. A variety of prostheses are used in stapedotomy, but this review focuses on the Nitinol prosthesis, the Causse Loop Piston prosthesis, and the Big Easy Piston prosthesis, comparing their effectiveness in improving postoperative hearing thresholds. The primary measure of hearing improvement is the air-bone gap (ABG) closure, calculated as the difference between preoperative and postoperative ABG. Based on these values, it was concluded that there is no significant difference in postoperative hearing outcomes among the three compared types of prostheses. The type of surgical approach and the choice of prosthesis must be made according to the individual characteristics of the patient.

• Keywords: otoskleroza; kirurgija; stapedotomija; stapedektomija; proteza; ishod
• Keywords (english): otosclerosis; surgery; stapedotomy; stapedectomy; prosthesis; outcome
• Language: croatian
• URN:NBN: urn:nbn:hr:105:946978
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-07-02 21:52:05