Pacijenti s intoksikacijama u Hitnom prijemu Kliničkog bolničkog centra Zagreb

master's thesis

• Title (english): Patients with intoxications in the Emergency Department of University Hospital Centre Zagreb
• Author: Iva Jurić
• Mentor: Ivan Gornik (mentor)
• Committee member: Robert Likić (predsjednik povjerenstva)
• Committee member: Marija Bakula (član povjerenstva)
• Committee member: Ivan Gornik (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Emergency Medicine

Abstract

Pacijenti s intoksikacijama čest su slučaj na hitnome prijemu. Njihova prezentacija ovisi o vrsti toksične tvari i dozi kojoj su bili izloženi. Određene tvari mogu uzrokovati karakteristične skupine simptoma koji se nazivaju toksidromi. U većini slučajeva liječenje je simptomatsko. Cilj ovoga rada bio je analizirati karakteristike i kliničke podatke pacijenata s intoksikacijama na Hitnom prijemu KBC-a Zagreb.
Retrospektivno je analizirano 138 pacijenata Objedinjenog hitnog bolničkog prijema Kliničkog bolničkog centra Zagreb u razdoblju od šest mjeseci s dijagnozom intoksikacije. Iz nalaza su prikupljeni demografski i klinički podaci. Radi lakše analize podataka intoksikacije su podijeljene u pet kategorija prema vrsti toksične tvari; alkohol, psihotropni lijekovi, ostali lijekovi, sredstva ovisnosti i ostale intoksikacije.
Pacijenti s intoksikacijama činili su 0,8% svih ne-kirurških pacijenata na Hitnom prijemu. Najčešće su bile intoksikacije alkoholom s 47,8% slučajeva, a zatim intoksikacije psihotropnim lijekovima s 18,1% slučajeva. Intoksikacije sredstvima ovisnosti i ostale intoksikacije bile su podjednako zastupljene, dok su najrjeđe bile intoksikacije ostalim lijekovima. Kod psihotropnih lijekova najčešći uzrok otrovanja bili su benzodiazepini, koji su nakon alkohola druga najzastupljenija tvar u ovom istraživanju. Većina intoksikacija bile su namjerne, uglavnom su imale lakšu kliničku sliku i dobar ishod.
Liječnici na hitnom prijemu susreću se s raznim vrstama intoksikacija, od kojih su najčešće intoksikacije alkoholom i lijekovima. Klinička slika može varirati od blagih simptoma do životno ugrožavajućih stanja. Zbog toga je potrebno dobro planiranje i edukacija, za što ovaj rad može dati temelje.

Abstract (english)

Patients with intoxications are a common case in the emergency department. Their clinical presentation depends on the type of toxic substance and the dose to which they were exposed. Certain substances can cause characteristic groups of symptoms known as toxidromes. Treatment is in most cases symptomatic. The aim of this study was to analyse the characteristics and clinical data of patients with intoxications in the Emergency Department of University Hospital Centre Zagreb.
A retrospective analysis was conducted on 138 patients of the Emergency Department of UHC Zagreb over a six-month period with a diagnosis of intoxication. Demografic and clinical data were collected from the patient's medical records. For easier data analysis, intoxications were divided into five categories according to the type of toxic substance; alcohol, psychotropic drugs, other medications, addictive substances and other intoxications.
Patients with intoxications comprised 0,8% od all non-surgical patients in the Emergency Department. The most common were alcohol intoxications, accounting for 47,8% of cases, followed by psychotropic drug intoxications at 18,1%. Intoxications with addictive substances and other intoxications were equally represented, while the least common were intoxications with other drugs. Among psychotropic drugs, benzodiazepines were the most common cause of poisoning, making them the second most prevalent substance in this study, after alcohol. Most intoxications were intentional, generally presented with mild symptoms, and had a good outcome.
Doctors in the emergency department encounter various types of intoxications, with alcohol and drug intoxications being the most common. Clinical presentation can range from mild symptoms to life-threatening conditions. Therefore, good planning and education are necessary, for which this study can provide a foundation.

• Keywords: Hitni prijem; Intoksikacija; Pacijenti; Toksična tvar
• Keywords (english): Emergency Department; Intoxication; Patients; Toxic Substance
• Language: croatian
• URN:NBN: urn:nbn:hr:105:448369
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-07-03 20:12:02