Painful Trigeminal Neuropathy

master's thesis

• Title (croatian): Bolna trigeminalna neuropatija
• Author: Victor Maximilian Markowitz
• Mentor: Jana Kogler (mentor)
• Committee member: Jana Kogler (predsjednik povjerenstva)
• Committee member: Ivan Adamec (član povjerenstva)
• Committee member: Dinko Tonković (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities); Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Anesthesiology and Reanimatology

Abstract

Painful trigeminal neuropathy is a potentially debilitating yet not well known neurological disease. Its hallmarks are specific sensory abnormalities and persistent facial pain. This review consolidates current knowledge on its symptoms, underlying causes, diagnostic challenges including the differential diagnosis, and treatment options linked to this condition.
The pathognomonic symptoms of painful trigeminal neuropathy help in correctly diagnosing this condition. These include sensory disturbances of painful trigeminal neuropathy, such as hypoesthesia, hyperesthesia, itching symptoms, taste alterations as well as motor function disturbance of the jaw. Depending on which specific branches of the trigeminal nerve are involved in each patient, the symptoms can differ accordingly. Therefore, understanding of the distribution and nature of the symptoms of painful trigeminal neuropathy is crucial for diagnosis.
The pathophysiology is influenced by a broad range of etiological events, including infections, trauma, systemic illnesses, and surgical procedures. To distinguish painful trigeminal neuropathy from other illnesses causing facial pain, such as trigeminal neuralgia, a comprehensive clinical evaluation and imaging procedures, including magnetic resonance imaging, are necessary for the diagnosis process. Painful trigeminal neuropathy is treated individually with a range of approaches, from minimally invasive and medicinal therapy to more involved forms of care.

Abstract (croatian)

Bolna trigeminalna neuropatija je potencijalno iscrpljujuća, ali nedovoljno poznata neurološka bolest. Njegova obilježja su specifične senzorne abnormalnosti i stalna bol lica. Ovaj pregled konsolidira trenutno znanje o njegovim simptomima, temeljnim uzrocima, dijagnostičkim izazovima uključujući diferencijalnu dijagnozu i mogućnostima liječenja povezanima s ovim stanjem.
Patognomonični simptomi bolne trigeminalne neuropatije pomažu u ispravnom dijagnosticiranju ovog stanja. To uključuje senzorne poremećaje bolne trigeminalne neuropatije, kao što su hipoestezija, hiperestezija, simptomi svrbeža, promjene
okusa kao i poremećaj motoričke funkcije čeljusti. Ovisno o tome koje su specifične grane trigeminalnog živca uključene u svakog pacijenta, simptomi se mogu razlikovati u skladu s tim. Stoga je razumijevanje distribucije i prirode simptoma bolne trigeminalne neuropatije ključno za dijagnozu.
Na patofiziologiju utječe širok raspon etioloških događaja, uključujući infekcije, traume, sistemske bolesti i kirurške zahvate. Kako bi se bolna neuropatija trigeminusa razlikovala od drugih bolesti koje uzrokuju bol u licu, kao što je neuralgija trigeminusa, potrebna je sveobuhvatna klinička procjena i postupci snimanja, uključujući magnetsku rezonanciju, za proces dijagnoze. Bolna trigeminalna neuropatija liječi se individualno nizom pristupa, od minimalno invazivne i medikamentozne terapije do složenijih oblika skrbi.

• Keywords: Trigeminal Neuralgia; Hypesthesia; Hyperesthesia; Nervous System Diseases
• Keywords (croatian): Trigeminalna neuralgija; hipestezija; hiperestezija; bolesti živčanog sustava
• Language: english
• URN:NBN: urn:nbn:hr:105:599110
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-18 09:36:59