Ekvivalent: Epidemiološke karakteristike i čimbenici povezani sa smrtnošću teško opečenih bolesnika – iskustvo hrvatskog opeklinskog centra

professional thesis

• Title (english): Equivalent: Epidemiological characteristics and factors associated with mortality in severely burned patients – Croatian national burn center report
• Author: Agata Škunca
• Mentor: Tomislav Radočaj (mentor)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-09-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Anesthesiology and Reanimatology

Abstract

The authors conducted a single-center retrospective study during the last 6.5 years. The study aimed to describe demographic data of burn patients in the Croatian Burn Center and investigate factors affecting mortality for the first time after the Center was established. The study included 109 severely burned patients with a total body surface area (TBSA) burned ≥20%, admitted to the burn intensive care unit. The relationship between the fatal outcome and age, sex, comorbidity, mechanism of injury, TBSA burned, and inhalation injury was investigated. The mean patient age was 54.50±20.21 years and the mean TBSA burned was 42.48±18.64%, with the mortality rate of 50%. The results demonstrated that patients with 2 or more comorbidities compared with those with no comorbidities had a higher chance of lethal outcome (p<0.0001). With an increase of TBSA by 1%, the odds of lethal outcome are expected to increase by 7% (p<0.0001). Other variables included in the analysis did not show statistical significance. TBSA percentage is a well-known predictor of mortality and numerous studies indicate an association between comorbidities and mortality but there are conflicting results about other demographic factors and injury characteristics.

Abstract (croatian)

Provedena je prva retrospektivna studija u tercijarnom centru u Hrvatskoj u posljednjih 6,5 godina s ciljem opisivanja demografskih podataka te čimbenika koji utječu na smrtnost teško opečenih bolesnika. U istraživanje je uključeno 109 teško opečenih bolesnika s ukupnom opečenom površinom ≥20%, hospitaliziranih u Jedinici intenzivnog liječenja. Analizirana je povezanost smrtnog ishoda i dobi, spola, supostojećih bolesti, mehanizma ozljede, postotka opečene površine i prisutnosti inhalacijske ozljede. Srednja dob bolesnika uključenih u istraživanje bila je 54,50±20,21 godina, srednja vrijednost postotka opečene površine bila je 42,48±18,64%, a smrtnost je iznosila 50%. Rezultati pokazuju veće izglede za smrtni ishod kod bolesnika s 2 ili više supostojećih bolesti u odnosu na one bez takvih bolesti (p<0,0001). Porastom postotka opečene površine kože za 1% izgledi za smrtni ishod rastu za 7% (p<0,0001). Analizom nije nađena statistički značajna razlika za ostale varijable. Postotak opečene površine je dobro poznati prediktor smrtnosti i brojne studije ukazuju na povezanost supostojećih bolesti i smrtnosti, dok su za ostale demografske čimbenike i značajke ozljede rezultati studija oprečni.

• Keywords: Opekline; epidemiologija; Hrvatska; smrtnost; odrasli
• Keywords (english): Burns; Epidemiology; Croatia; Mortality; Adult
• Language: english
• URN:NBN: urn:nbn:hr:105:870951
• Study programme: Title: Anesthesiology, reanimatology and intensive care medicine; Study programme type: university; Study level: postgraduate specialist; Academic / professional title: sveučilišni/a magistar/magistra anesteziologije, reanimatologije i intenzivne medicine (sveučilišni/a magistar/magistra anesteziologije, reanimatologije i intenzivne medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-28 09:30:17