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Scientific paper - Review paper
The endocannabinoid system in appetite regulation and treatment of obesity
Pharmacology Research & Perspectives, 12 (2024), 5; e70009. https://doi.org/10.1002/prp2.70009
Kurtov, Marija; Rubinić, Igor; Likić, Robert

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Kurtov, M., Rubinić, I. & Likić, R. (2024). The endocannabinoid system in appetite regulation and treatment of obesity. Pharmacology Research & Perspectives, 12. (5). doi: 10.1002/prp2.70009

Kurtov, Marija, et al. "The endocannabinoid system in appetite regulation and treatment of obesity." Pharmacology Research & Perspectives, vol. 12, no. 5, 2024. https://doi.org/10.1002/prp2.70009

Kurtov, Marija, Igor Rubinić and Robert Likić. "The endocannabinoid system in appetite regulation and treatment of obesity." Pharmacology Research & Perspectives 12, no. 5 (2024). https://doi.org/10.1002/prp2.70009

Kurtov, M., Rubinić, I. and Likić, R. (2024) 'The endocannabinoid system in appetite regulation and treatment of obesity', Pharmacology Research & Perspectives, 12(5). doi: 10.1002/prp2.70009

Kurtov M, Rubinić I, Likić R. The endocannabinoid system in appetite regulation and treatment of obesity. Pharmacology Research & Perspectives [Internet]. 2024 September 18 [cited 2025 April 03];12(5). doi: 10.1002/prp2.70009

M. Kurtov, I. Rubinić and R. Likić, "The endocannabinoid system in appetite regulation and treatment of obesity", Pharmacology Research & Perspectives, vol. 12, no. 5, September 2024. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:781232. [Accessed: 03 April 2025]

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Metadata
Title (english)The endocannabinoid system in appetite regulation and treatment of obesity
AuthorMarija Kurtov
AuthorIgor Rubinić
AuthorRobert Likić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The endocannabinoid system (ECS) is a complex cell‐signaling system that is responsible for maintaining homeostasis by modulating various regulatory reactions in response to internal and environmental changes. The influence of ECS on appetite regulation has been a subject of much recent research, however, the full extent of its impact remains unknown. Current evidence links human obesity to ECS activation, increased endocannabinoid levels in both central and peripheral tissues, along with cannabinoid receptor type 1 (CBR1) up‐regulation. These findings imply the potential pharmacological use of the ECS in the treatment of obesity. Here, we present various pathophysiological processes in obesity involving the ECS, highlighting different pharmacological options for modulating endocannabinoid activity to treat obesity. However, the potential of those pharmacological possibilities remains under investigation and requires further research.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePharmacology Research & Perspectives
Numberingvol. 12, no. 5, e70009
p-ISSN2052-1707
e-ISSN2052-1707
DOIhttps://doi.org/10.1002/prp2.70009
URN:NBNurn:nbn:hr:105:781232
Publication2024-09-18
Document URLhttps://bpspubs.onlinelibrary.wiley.com/doi/10.1002/prp2.70009
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2025-03-20 09:09:02