Rizični čimbenici i prognostičko značenje fibrilacije atrija u akutnom infarktu miokarda

master's thesis

• Title (english): Risk factors and prognostic significance of atrial fibrillation in acute myocardial infarction
• Author: Dino Mikulić
• Mentor: Zdravko Babić (mentor)
• Committee member: Diana Delić-Brkljačić (predsjednik povjerenstva)
• Committee member: Jasenka Markeljević (član povjerenstva)
• Committee member: Zdravko Babić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2017-07-14, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Fibrilacija atrija (AF) je najčešća srčana aritmija i povezana je s povećanim kardiovaskularnim morbiditetom i mortalitetom. AF predstavlja golem ekonomski teret za razvijene zemlje koji se mjeri u milijardama dolara. Prevalencija AF kod pacijenata s akutnim infarktom miokarda (AMI) je između 2,3 i 22,6%. Mnogi su rizični faktori za AF, prvenstveno starija dob, koji ne samo da povećavaju rizik za AF nego također utječu i na ishod liječenja AMI. Postoji opći konsenzus oko toga da AF predstavlja nezavisni rizični faktor za povećani mortalitet u AMI. Unatoč tome, postoje brojna istraživanja koja daju različite rezultate koji se tiču AF i njenog značaja kao rizičnog faktora. Uobičajeno je u literaturi AF u AMI podijeljena u dvije kategorije: new onset (novonastala), koja se uglavnom dijeli na paroksizmalnu i perzistentnu AF, te permanentnu AF. Cilj ovog preglednog rada je sistematska analiza rezultata istraživanja o AF u AMI i njihova sumacija.

Abstract (english)

Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased cardiovascular morbidity and mortality. AF represents enormous economic burden for the developed countries that is measured in billions of dollars. The prevalence of AF in patients with acute myocardial infarction (AMI) is between 2.3 and 22.6%. There are many risk factors for AF, primarily the older age, which can not only increase the risk for AF but also affect the outcome of acute myocardial infarcion treatment. There is a general unanimity towards AF being an independent risk factor for the increased mortality in the setting of AMI. Despite this, there are many trials showing different results considering its significance as a risk factor. In the literature, AF in AMI is usualy divided in two main categories: new onset, which most often consists of paroxysmal and persistent AF, and permanent AF. The goal of this overview is a systematic analysis of the results of trials considering AF in the setting of AMI and their summation.

• Keywords: fibrilacija atrija; akutni infarkt miokarda; mortalitet; rizični čimbenici
• Keywords (english): atrial fibrillation; acute myocardial infarction; mortality; risk factors
• Language: croatian
• URN:NBN: urn:nbn:hr:105:560148
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2018-03-13 08:09:00