Dijagnostika i liječenje dobroćudnih novotvorina jajnika

master's thesis

• Title (english): Diagnosis and management of benign neoplasms of the ovary
• Author: Lea Cecelja
• Mentor: Vladimir Banović (mentor)
• Committee member: Držislav Kalafatić (predsjednik povjerenstva)
• Committee member: Željko Duić (član povjerenstva)
• Committee member: Vladimir Banović (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Benigne novotvorine jajnika su najčešće novotvorine jajnika, a u njih ubrajamo funkcionalne ciste te dobroćudne novotvorine jajnika koje mogu imati različit omjer cističnih i solidnih komponenti. Češće se pojavljuju u žena reproduktivne dobi, dok rizik za malignitet raste sa dobi. Klinička prezentacija im može biti asimptomatska i simptomatska, a jakost simptoma ovisi o veličini i lokalizaciji novotvorine. Svjetska zdravstvena organizacija klasificira novotvorine jajnika po njihovoj histogenezi. U dijagnostici i diferencijaciji benignih od malignih novotvorina jajnika pomaže nam nekoliko informacija koje se mogu dobiti kvalitetno uzetom anamnezom i fizikalnim pregledom. Sljedeći korak u daljnjoj obradi je ultrazvuk. Zbog potrebe za standardizacijom terminologije i pomoći pri diferencijaciji koja se koristi pri opisu ultrazvučnog nalaza, Internacionalna studija za analizu ovarijskih tumora je razvila listu jednostavnih pravila, definicija i opisa koji pomažu karakterizirati tvorbe jajnika. Temeljem opisa ultrazvučnog nalaza pacijentica se usmjeruje na određivanje CA 125 i po potrebi na ostale slikovne metode. Postoje tri mogućnosti liječenja, a to su terapija strpljivog čekanja, farmakološka, i kirurška terapija. Odluka o liječenju ovisi o uzetoj anamnezi, dijagnozi, dobi pacijentice, čimbenicima rizika i kliničkoj prezentaciji.

Abstract (english)

Benign ovarian abnormalities are most common of ovarian neoplasms, including functional cysts and benign ovarian neoplasms which may have a different ratio of cystic and solid components. They occur more often in women of reproductive age, while the risk of malignancy increases with age. Clinical presentation can be both asymptomatic and symptomatic, while symptom intensity depends on the size and localization of the neoplasm. The World Health Organization classifies ovarian neoplasms by their histogenesis. Through anamnesis and physical examination, we are able to provide some helpful information for the diagnostics and differentiation of benign from malignant ovary neoplasms. The next step in further processing is ultrasonography. Due to the need for standardization of terminology used in the description of the ultrasound findings, the International Ovarian Tumor Analysis group has developed a list of simple rules, definitions and descriptions that help characterize ovarian formations. Based on the description of the ultrasonic finding, the patient is directed towards determining the CA 125 and other imaging methods if necessary. There are three possibilities of treatment, such as pharmacological and surgical therapy, and patience. The decision on treatment depends on well received history, diagnosis, patient age, risk factors, and clinical presentation.

• Keywords: benigne novotvorine jajnika; funkcionalne ciste; ultrazvuk; dob; kirurško liječenje
• Keywords (english): benign ovarian neoplasms; functional cysts; ultrasonography; age; surgical treatment
• Language: croatian
• URN:NBN: urn:nbn:hr:105:315491
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2019-11-15 11:42:58