| Abstract | In-stent restenoza (ISR) predstavlja veliki problem u pacijenata nad kojima je provedena PCI. Čak u do 30% pacijenata ISR se prezentira kao infarkt miokarda. U ovo retrospektivno istraživanje uključeno je 1768 ispitanika nad kojima je izvršena PCI u KB Merkur od 2014. do 2018. godine, a koji su podijeljeni u 2 skupine ovisno o tome je li PCI-om tretirana ISR ili neka druga lezija. Skupine su proučavane kako bi se pronašle razlike u kliničkim parametrima koji su dosad istraživani kao rizični čimbenici za ISR (dijabetes, hipertenzija, hiperlipidemija, pušenje, IM u anamnezi, CABG u anamnezi), kao i razlike u proceduralnim parametrima same intervencije (broj žica, balona i stentova, duljina trajanja fluoroskopije, količina kontrasta i uporaba DEB). Statistički značajne razlike između skupine s ISR i skupine bez ISR uočene su za hiperlipidemiju (98,85% naspram 88,11%; p=0,002), IM (54,02% naspram 38,63%; p=0,004), pušenje (16,09% naspram 25,77%; p=0,043), broj stentova (79,31% ISR skupine nije imalo ugrađen niti jedan stent, dok je 64,17% skupine bez ISR imalo ugrađen jedan stent; p<0,001), broj žica (u 93,10% ISR skupine naspram 69,53% skupine bez ISR korištena je 1 žica uvodnica; p<0,001), broj balona (kod 37,78% ISR skupine naspram 21,08% skupine bez ISR korišteno je 2 balona; p<0,001), duljina trajanja fluoroskopije (8 minuta naspram 11 minuta i 37 sekundi; p=0,007), količina kontrasta (127,32mL, naspram 151,9mL; p=0,002) i uporaba DEB-a (68,97% naspram 6,58%). |
| Abstract (english) | In-stent restenosis (ISR) represents a major problem in patients who underwent PCI. Up to 30% of ISR patients present as myocardial infarction. This retrospective study included 1768 patients who underwent PCI in The Merkur Clinical Hospital between 2014 and 2018 and who were separated in two groups based on whether PCI was used to treat ISR or some other lesion. It examined the two groups in order to identify the differences in clinical parameters that were in previous studies investigated as risk factors for ISR (diabetes, hypertension, hyperlipidaemia, smoking, IM, CABG in anamnestic history), as well as the differences in some procedural parameters (number of guide wires, balloons and stents, duration of fluoroscopy, amount of contrast, use of DEBs). Statistically significant difference between ISR and non-ISR group was observed for hyperlipidaemia (98,85% as opposed to 88,11%; p=0,002), MI (54,02% compared to 37,63%; p=0,004), smoking (16,09% compared to 25,77%; p=0,043), number of stents (79,31% of the ISR group had 0 stents implanted, whereas 64,17% of the non-ISR group had 1 stent implanted; p=0,000), number of wires (93,10% of the ISR group, as opposed to 69,53% of the non-ISR group were treated by using 1 wire; p<0,001), number of balloons (2 balloons were used in 37,78% of the ISR group compared to 21,08% in the non-ISR group; p<0,001), duration of fluoroscopy (8 minutes compared to 11 minutes and 37 seconds; p=0,007), amount of contrast (127,32mL compared to 151,9mL; p=0,002) and use of DEBs (68,97% compared to 6,58%). |
