Operativno liječenje tumora pontocerebelarnog kuta

master's thesis

• Title (english): Surgical treatment of pontocerebellar angle tumors
• Author: Marko Petrić
• Mentor: Goran Mrak (mentor)
• Committee member: Josip Paladino (predsjednik povjerenstva)
• Committee member: Tomislav Meštrović (član povjerenstva)
• Committee member: Goran Mrak (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Surgery); Zagreb
• Defense date and country: 2014-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery

Abstract

Tumori pontocerebelarnog kuta čine gotovo desetinu svih intrakranijalnih tumora. Zbog određenih značajki u kliničkoj slici i pristupu u liječenju, ove tumore mnogi autori svrstavaju u zajedničku skupinu u neurokirurgiji. Do 85% svih tumora pontocerebelarnog kuta čine neurinomi akustičnog živca. Lezije u pontocerebelarnom kutu predstavljaju poseban izazov u diferencijalnoj dijagnozi i kirurškom liječenju zbog specifičnog anatomskog smještaja i vrlo raznolike etiologije. Unatoč svojoj kompleksnosti, a sukladno rezultatima najnovijih kliničkih istraživanja, u modernoj neurokirurgiji očekuje se uspješno prepoznavanje kao i praćenje i liječenje progresije lezija pontocerebelarnog kuta. Kod liječenja se može odabrati opservacija, otvorena operacija pomoću mikrokirurških metoda te stereotaksijska radiokirurgija. Kod otvorene operacije postoji nekoliko operativnih pristupa pontocerebelarnom području čiji odabir ovisi o anatomskim varijacijama i veličini tumora. Važno je očuvanje funkcije živaca koji svojim tokom prolaze kroz pontocerebelarni kut, jer oštećenja mogu dovesti do značajnog smanjenja kvalitete života pacijenta. U konačnici kirurško liječenje dovodi do niskog morbiditeta i zanemarivog mortaliteta operiranih bolesnika.

Abstract (english)

Cerebellopontine angle tumors make up almost tenth of all intracranial tumors. Because of the specific clinical presentation and treatment plan, many authors sort these tumors in the same group in neurosurgery. In up to 85% of the cases all diagnosed cerebellopontine angle tumors are vestibular schwannoma. Cerebellopontine angle lesions represent special challenge in diferential diagnosis and surgical treatment because of their specific anatomical position and extremely diverse etiology. Despite their complexity and in accordance with new clinical research their recognition, follow up and treatment of progression of lesions of cerebellopontine angle is expected in modern neurosurgery. Neurosurgeon can choose to observe, surgically treat the lesion with microsurgical techniques or with methods of stereotactic neurosurgery. For open surgery neurosurgeon can choose several different approaches to cerebellopontine angle, and that choice depends on anatomical variations and size of the tumor. It is important to conserve function of the cranial nerves which pass through cerebellopontine angle, because their lesions can significantly impair quality of life of the patient. In the end, treatment leads to low morbidity and negligible mortality in patients.

• Keywords: pontocerebelarni kut; neurokirurgija; stereotaksijska neurokirurgija; švanom; meningeom
• Keywords (english): cerebellopontine angle; neurosurgery; stereotactic neurosurgery; vestibular schwannoma; meningeoma
• Language: croatian
• URN:NBN: urn:nbn:hr:105:194571
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-10-29 10:24:26