Intenzivno liječenje bolesnica s eklampsijom

master's thesis

• Title (english): Intensive care management of women with eclampsia
• Author: Jakica Ana Živković
• Mentor: Slobodan Mihaljević (mentor)
• Committee member: Daniela Bandić Pavlović (predsjednik povjerenstva)
• Committee member: DINKO TONKOVIĆ (član povjerenstva)
• Committee member: Slobodan Mihaljević (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Anesthesiology and Reanimatology

Abstract

Eklampsija je po život opasno stanje, ne samo za trudnicu, već i za njeno nerođeno
dijete. Poznata je još od doba Hipokrata, od koga datira i prvi opis ovoga stanja. Sam
naziv „eklampsija“ dolazi od grčke riječi za izraz bljesnuti, kojim se nastojala objasniti
iznenadna pojava konvulzija. Eklampsija se definira kao pojava konvulzija, najčešće
pred porod, u trudnica sa simptomima preeklampsije, odnosno hipertenzijom i
proteinurijom nastalima nakon 20. tjedna gestacije. Prema tome, bez preeklampsije
nema ni eklampsije, tako da se eklampsija može smatrati progresijom same
preeklampsije, a ne toliko zasebnim entitetom. Konvulzije koje se javljaju u eklampsiji
su toničko – kloničkog tipa i obično traju jednu minutu. Brojne su komplikacije vezane
uz eklampsiju, kao što su aspiracijska pneumonija, moždano krvarenje, zatajenje
bubrega i srčano zatajenje. Preeklampsija i eklampsija dio su veće grupe poznate
kao hipertenzivni poremećaji u trudnoći. U liječenju eklampsije primarno je zaustaviti
konvulzije, što se postiže davanjem magnezijevog sulfata, a nakon toga je nužno
stabilizirati krvni tlak antihipertenzivnim lijekovima. Usprkos svih napredaka u
medicini i svih modernih tehnologija i terapija na raspolaganju, u slučaju eklampsije,
jedina konačna terapija je porod. I dan danas, eklampsija je važan uzrok smrtnosti
majki, ali i djece u svijetu. Kao što se može vidjeti, brojni su izazovi stavljeni pred
liječnike koji skrbe o bolesnicama s eklampsijom, jedan od kojih je i činjenica da se,
osim za ženu, moraju brinuti i za zdravlje i dobrobit njenog djeteta.

Abstract (english)

Eclampsia is a life – threatening disease, which affects not only the mother, but her
unborn child as well. We have known about it since the time of Hippocrates, who was
the first to describe this condition. The word „eclampsia“ derives from the Greek term
for lightening, attempting to explain the abrupt onset of convulsions. Eclampsia is
defined as the onset of convulsion, mostly antepartum, in women with sympthoms of
pre-eclampsia, meaning with hypertension and proteinuria that occured after the 20th
week of gestation. Accordingly, without pre-eclampsia there is no eclampsia,
therefore it can be regarded as progression of pre-eclampsia, rather than its own
entity. The seizures that occur in eclampsia are of clonic – tonic type and they usually
last for one minute. Numerous complications, like aspiration pneumonia, cerebral
hemorrhage, kidney failure, and cardiac arrest, are associated with eclampsia. Preeclampisa
and eclampsia are a part of a larger group of conditions known as
hypertensive disorders of pregnancy. The primary goal in treating eclampsia is to
stop seizures by administering magnesium sulfate, and afterwards to stabilize the
blood pressure with an antihypertensive therapy. Despite all the progress made in
medicine, and all of modern tehnologies and therapy options, when considering
eclampsia, the only definite treatment option is giving birth. Even now, eclampsia is
an important cause of death amongst mothers, and newborns all around the world.
As can be observed, there are many challanges that physicians who participate in the
care of eclamptic women have to face, one of which is the fact that they have, not
only the mother, but her childs' health and wellbeing to take care of as well.

• Keywords: eklampsija; preeklampsija; konvulzije; magnezijev sulfat; porod
• Keywords (english): eclampsia; pre-eclampsia; convulsions; magnesium sulfate; child birth
• Language: croatian
• URN:NBN: urn:nbn:hr:105:051187
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-02-04 08:27:55