Prevalence of allergic rhinitis and asthma in patients who underwent sinus surgery

master's thesis

• Title (croatian): Učestalost alergijskog rinitisa i astme kod pacijenata nakon operacije sinusa
• Author: Nika Puževski
• Mentor: Tomislav Baudoin (mentor)
• Committee member: Tomislav Baudoin (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Livije Kalogjera (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2019-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

OBJECTIVES: The aim of this study was to assess the prevalence of allergies or asthma in CRS patients who underwent ESS within treatment for sinonasal disease at the Department of ORL and HNS, Sisters of Charity University Hospital in Zagreb and compare the results to other studies. ----- METHODS: One hundred patients from ages 10 to 75 who underwent endoscopic sinus surgery in 2018, due to CRS were retrospectively reviewed. We analyzed demographics, CRS phenotypes, comorbidity of asthma and allergy and septal deformation together with different surgical procedures were collected from medical records. ----- RESULTS: From 100 patients that were included in our study 54% of the participants (42 males and 12 females) are diagnosed with CRSwNP and 46% (23 males and 23 females) with CRSsNP. Patients having CRSwNP show slightly higher rates of allergies of any type and asthma, however they have lower incidence of septal deformation. Furthermore, male predominance is shown both in total studied group (65%) as well as in group with allergies (70.73%) while FESS with polipectomy is shown to be the most common type of surgical procedure. ----- CONCLUSION: We can conclude that comorbidity of asthma and allergy has higher prevalence in patients with CRSwNP, while septal deformation in patients with CRSsNP.

Abstract (croatian)

CILJEVI: Cilj ovog istraživanja bio je procijeniti učestalost alergija ili astme kod bolesnika s kroničnim rinosinusitisom (KRS), koji su podvrgnuti endoskopskoj operaciji sinusa kao dio liječenja sinonazalne bolesti na Klinici za otorinolarigologiju i kirurgiju glave i vrata, KBC Sestre milosrdnice, i usporediti rezultate s drugim studijama. ----- METODE:
Retrospektivno su pregledane povijesti bolesti od sto pacijenata u dobi od 10 do 75 godina koji su tijekom 2018. godine bili podvrgnuti endoskopskoj operaciji sinusa. Analizirali smo demografske karakteristike, fenotipove bolesti, prevalenciju astme i alergijskih bolesti u ispitanika te vrste kirurških zahvata. ----- REZULTATI: Od 100 bolesnika koji su bili uključeni u naše istraživanje, 54% ispitanika (42 muškarca i 12 žena) dijagnosticiran je kronični rinosinuitis s nazalnom polipozom (KRSsNP), dok je 46% ispitanika (23 muškarca i 23 žene) dijagnosticiran kronični rinosinuitis bez nazalne polipoze (KRSbNP). Bolesnici koji imaju KRSsNP pokazuju nešto veću sklonost alergijama bilo koje vrste i astmi, ali imaju manju učestalost septalne deformacije. Više je bilo muškaraca ukupno(65%) kao i u skupini ispitanika s alergijama(70.73%) , a FESS s polipektomijom je najčešće izvođen zahvat (42%). ----- ZAKLJUČAK: Možemo zaključiti da je komorbiditet astme i alergije učestaliji u bolesnika s KRSsNP, a septalna deformacija u bolesnika s KRSbNP.

• Keywords: chronic rhinosinusitis; allergy; asthma; endoscopic sinus surgery; ESS
• Keywords (croatian): kronični rinosinusitis; alergija; astma; endoskopska sinusna kirurgija
• Language: english
• URN:NBN: urn:nbn:hr:105:802925
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2020-07-20 09:22:01