Histološka evaluacija tkiva nakon laparoskopske cistektomije zbog endometrioma jajnika

master's thesis

• Title (english): Histological evaluation of the tissue after laparoscopic cystectomy of the ovary due to endometrioma
• Author: Iva Šamec
• Mentor: Mario Ćorić (mentor)
• Committee member: Vladimir Banović (predsjednik povjerenstva)
• Committee member: Lovorka Batelja-Vuletić (član povjerenstva)
• Committee member: Mario Ćorić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Gynecology and Obstetrics); Zagreb
• Defense date and country: 2020-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Endometriom je pojam koji se odnosi na endometriozu jajnika. To su jedne od najčešćih cističnih tvorbi koje se nalaze intraoperacijski na jajniku. Simptomi karakteristični za endometriozu općenito su dismenoreja, dispareunija, te bolovi u zdjelici koji nisu povezani s menstruacijom. Razvojem kirurških tehnika laparoskopska cistektomija postaje metoda prvog izbora u liječenju endometrioma, a najčešće korištena minimalno invazivna metoda je ekscizija ciste, ljuštenje, odnosno "stripping" tehnikom. Cilj ovog rada je dokazati da je udio zdravog tkiva jajnika veći u histološki analiziranim uzorcima nakon cistektomije zbog endometrioma nego nakon cistektomije zbog druge etiologije te ukazati na važnost laparoskopske tehnike, iskustva operatera, ali i opravdanosti operacijskog zahvata u pacijentica s endometriomima jajnika. U analizu je uključeno 676 pacijentica s prosječnom dobi od 31,4 godine koje su nakon kliničke dijagnoze ciste jajnika podvrgnute laparoskopskoj cistektomiji u razdoblju od siječnja 2014. godine do listopada 2019. godine. Rezultati su pokazali da 84,5% uzoraka nakon laparoskopske cistektomije endometrioma sadrži malo zdravog tkiva jajnika. U 30,5% slučajeva nakon cistektomije cista jajnika zbog druge etiologije u uzorku nema zdravog tkiva jajnika.
Na kraju možemo zaključiti da je u uzorcima nakon laparoskopske cistektomije endometrioma vidljivo više zdravog tkiva jajnika nego u uzorcima nakon laparoskopske cistektomije zbog cista druge etiologije.

Abstract (english)

Endometriomas are a common cause of gynecologic morbidity and the most common ovarian cysts encountered during surgery.The main symptoms that patients encounter is pain like dysmenorrhea, dyspareunia and pelvic pain that is not associated with menstruation. With the development of a surgical techniques, laparoscopic cystectomy remains the first-line of treatment for endometriotic cysts. The most common minimal invasive method is the cyst excision by stripping. Aim of this study was to prove that the share of healthy ovarian tissue is higher in histological analysis of samples after cystectomy due to endometrioma than after cystectomy due to other etiologies. Moreover, to point out the importance of laparoscopic technique, operator experience and also the justification of surgery in patients with ovarian endometrioma. The study included 676 patientswith age meanof 31.4 years which underwent laparoscopic cystectomy in period from January 2014 to October 2019 after the clinical diagnose of ovarian cysts. Results showed that 84.5% of samples after laparoscopic cystectomy of the endometrioma contain small portion of normal ovarian tissue. In 30.5% of samples after cystectomy of other etiologies cysts there is no ovarian tissue present. In conclusion, samples after laparoscopic cystectomy of endometrioma contain more norma
lovarian tissue than samples after laparoscopic cystectomy due to cysts of other etiologies.

• Keywords: endometriom; cistektomija; pričuva jajnika
• Keywords (english): endometrioma; cystectomy; ovarian reserve
• Language: croatian
• URN:NBN: urn:nbn:hr:105:343505
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-03-22 13:36:12