prikaz prve stranice dokumenta Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood a
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Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
Haematologica, 105 (2020), 6; 1507-1516. https://doi.org/10.3324/haematol.2019.243410
Bazarbachi, Ali; Bug, Gesine; Baron, Frederic; Brissot, Eolia; Ciceri, Fabio; Dalle, Iman Abou; Döhner, Hartmut; Esteve, Jordi; Floisand, Yngvar; Giebel, Sebastian; Gilleece, Maria; Gorin, Norbert-Claude; Jabbour, Elias; Aljurf, Mahmoud; Kantarjian, Hagop; Kharfan-Dabaja, Mohamed; Labopin, Myriam; Lanza, Francesco; Malard, Florent; Perić, Zinaida; Prebet, Thomas; Ravandi, Farhad; Ruggeri, Annalisa; Sanz, Jaime; Schmid, Christoph; Shouval, Roni; Spyridonidis, Alexandros; Versluis, Jurjen; Vey, Norbert; Savani, Bipin N; Nagler, Arnon; Mohty, Mohamad More authors...

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Bazarbachi, A., Bug, G., Baron, F., Brissot, E., Ciceri, F., Dalle, I. A. ... Mohty, M. (2020). Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Haematologica, 105. (6), 1507-1516. doi: 10.3324/haematol.2019.243410

Bazarbachi, Ali, et al. "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation." Haematologica, vol. 105, no. 6, 2020, pp. 1507-1516. https://doi.org/10.3324/haematol.2019.243410

Bazarbachi, Ali, Gesine Bug, Frederic Baron, Eolia Brissot, Fabio Ciceri, Iman Abou Dalle, Hartmut Döhner, et al. "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation." Haematologica 105, no. 6 (2020): 1507-1516. https://doi.org/10.3324/haematol.2019.243410

Bazarbachi, A., et al. (2020) 'Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation', Haematologica, 105(6), pp. 1507-1516. doi: 10.3324/haematol.2019.243410

Bazarbachi A, Bug G, Baron F, Brissot E, Ciceri F, Dalle IA, and sur.. Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation. Haematologica [Internet]. 2020 June [cited 2024 October 05];105(6):1507-1516. doi: 10.3324/haematol.2019.243410

A. Bazarbachi, et al., "Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation", Haematologica, vol. 105, no. 6, pp. 1507-1516, June 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:868776. [Accessed: 05 October 2024]

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Metadata
Title (english)Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with -internal tandem duplication: a position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
AuthorAli Bazarbachi
AuthorGesine Bug
AuthorFrederic Baron
AuthorEolia Brissot
AuthorFabio Ciceri
AuthorIman Abou Dalle
AuthorHartmut Döhner
AuthorJordi Esteve
AuthorYngvar Floisand
AuthorSebastian Giebel
AuthorMaria Gilleece
AuthorNorbert-Claude Gorin
AuthorElias Jabbour
AuthorMahmoud Aljurf
AuthorHagop Kantarjian
AuthorMohamed Kharfan-Dabaja
AuthorMyriam Labopin
AuthorFrancesco Lanza
AuthorFlorent Malard
AuthorZinaida Perić
AuthorThomas Prebet
AuthorFarhad Ravandi
AuthorAnnalisa Ruggeri
AuthorJaime Sanz
AuthorChristoph Schmid
AuthorRoni Shouval
AuthorAlexandros Spyridonidis
AuthorJurjen Versluis
AuthorNorbert Vey
AuthorBipin N Savani
AuthorArnon Nagler
AuthorMohamad Mohty
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
The FMS-like tyrosine kinase 3 (FLT3) gene is mutated in 25-30% of patients with acute myeloid leukemia (AML). Because of the poor prognosis associated with FLT3-internal tandem duplication mutated AML, allogeneic hematopoietic stem-cell transplantation (SCT) was commonly performed in first complete remission. Remarkable progress has been made in frontline treatments with the incorporation of FLT3 inhibitors and the development of highly sensitive minimal/measurable residual disease assays. Similarly, recent progress in allogeneic hematopoietic SCT includes improvement of transplant techniques, the use of haploidentical donors in patients lacking an HLA matched donor, and the introduction of FLT3 inhibitors as post-transplant maintenance therapy. Nevertheless, current transplant strategies vary between centers and differ in terms of transplant indications based on the internal tandem duplication allelic ratio and concomitant nucleophos-min-1 mutation, as well as in terms of post-transplant maintenance/consolidation. This review generated by international leukemia or transplant experts, mostly from the European Society for Blood and Marrow Transplantation, attempts to develop a position statement on best approaches for allogeneic hematopoietic SCT for AML with FLT3-internal tandem duplication including indications for and modalities of such transplants and on the potential optimization of post-transplant maintenance with FLT inhibitors.
Languageenglish
Publication typeProfessional paper - Professional paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleHaematologica
Numberingvol. 105, no. 6, pp. 1507-1516
p-ISSN0390-6078
e-ISSN1592-8721
DOIhttps://doi.org/10.3324/haematol.2019.243410
URN:NBNurn:nbn:hr:105:868776
Publication2020-06
Document URLhttp://www.haematologica.org/lookup/doi/10.3324/haematol.2019.243410
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2021-04-16 11:56:55