Kirurško liječenje hiperparatiroidizma

master's thesis

• Title (english): Surgical treatment of hyperparathyroidism
• Author: Andro Tarle
• Mentor: Vladimir Bedeković (mentor)
• Committee member: Davor Vagić (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Vladimir Bedeković (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

Četiri paratireoidne žlijezde su žlijezde s unutarnjim izlučivanjem, smještene na stražnjoj stijenci štitnjače. Njihova glavna uloga je izlučivanje PTH, hormona koji je glavni čimbenik održavanja fiziološke koncentracije kalcija u izvanstaničnim tekućinama. Pojačano djelovanje paratireoidnih žlijezda kod kojega dolazi do visoke koncentracije paratireoidnog hormona naziva se hiperparatireoidizam. Primarni hiperparatireoidizam nastaje zbog bolesti paratireoidnih žlijezda, dok sekundarni hiperparatireoidizam nastaje zbog neke druge bolesti koja dovodi do pojačane aktivnosti paratireoidnih žlijezda. U slučaju abnormalnih, povišenih koncentracija kalcija, dolazi do pojave kliničkih simptoma. Kirurški zahvat je prva metoda izbora u liječenju primarnog hiperparatireoidizma, a koristiti se može i u liječenju sekundarnog hiperparatireoidizma. Kirurško liječenje hiperparatireoidizma danas se najčešće obavlja minimalno invazivnim zahvatom koji ima mnoge prednosti u odnosu na ostale načine liječenja. Dok je u primarnom hiperparatireoidizmu kirurško liječenje metoda izbora, kod sekundarnog hiperparatireoidizma se obavlja u uznapredovalim stadijima, kada su iscrpljene sve ostale metode liječenja osnovne bolesti.

Abstract (english)

The four parathyroid glands are minute endocrine glands located on the posterior wall of the thyroid gland. Their main role is secreting of PTH, a hormone that is a major factor in maintaining the physiological concentration of calcium in extracellular fluids. Increased activity of the parathyroid glands when there is a high concentration of parathyroid hormone is called hyperparathyroidism. Primary hyperparathyroidism is caused by diseases of the parathyroid glands, while secondary hyperparathyroidism is caused by some other diseases that lead to increased activity of the parathyroid glands. In case of abnormal calcium concentrations, clinical symptoms may occur. Today, surgical treatment of hyperparathyroidism is a minimally invasive procedure that has many advantages over other procedures that can be used. Surgery is the method of choice in the treatment of primary hyperparathyroidism, and can also be used in the treatment of secondary hyperparathyroidism. While in primary hyperparathyroidism surgical treatment is the method of choice, in secondary hyperparathyroidism it must be performed in advanced stages, when all other methods of treating the underlying disease have been exhausted.

• Keywords: paratireoidne žlijezde; štitnjača; hiperparatireoidizam; kirurško liječenje
• Keywords (english): parathyroid glands; thyroid gland; hyperparathyroidism; surgical treatment
• Language: croatian
• URN:NBN: urn:nbn:hr:105:875393
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Public note: Pohranitelj objekta unio ključne riječi.
• Created on: 2021-05-10 11:18:55