Karakteristike bolesnika inficiranih i koloniziranih bakterijom mrsa u općoj bolnici zabok i bolnici hrvatskih veterana

master's thesis

• Author: Domagoj Karažija
• Mentor: Ana Budimir (mentor)
• Committee member: Zrinka Bošnjak (predsjednik povjerenstva)
• Committee member: Goran Tešović (član povjerenstva)
• Committee member: Ana Budimir (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Medical Microbiology and Parasitology); Zagreb
• Defense date and country: 2020-07-07, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Public Health and Health Care

Abstract

Uvod: Povećana proizvodnja te neracionalna potrošnja lijekova, a posebice
antibiotika, dovela je do prilagodbe bakterija koje uzrokuju određene kliničke slike
(bolest) tim antibioticima, koje u bolničkim sredinama uzrokuju bolničke infekcije. U
Republici Hrvatskoj (najčešća bolnička infekcija je ona izazvana virusom
Staphylococus aureus, a naziva se Staphylococcus aureus rezistentan na meticilin
(MRSA) koja je stvorila otpornost prema mnogim klasičnim antibioticima. MRSA
produljuje duljinu boravka bolesnika u bolnici, uzrokuje rizik od prijenosa infekcije
među zdravstvenim osobljem u bolnici te ostalim bolesnicima te ekonomski iscrpljuje
zdravstveni sustav. U radu je prikazano kretanje MRSA u Općoj bolnici Zabok i
bolnici hrvatskih veterana kroz razdoblje 2015.-2019. godine te su opisane
karakteristike MRSA oboljelih bolesnika.
Metodologija: Ispitivanje karakteristika bolesnika inficiranih i koloniziranih bakterijom
MRSA provedeno je retrospektivnim istraživanjem bolesnika koji su zaprimljeni u
Opću bolnicu Zabok I bolnicu hrvatskih veterana na bolničko liječenje u razdoblju
1.1.2015.-31.12.2019. godine, a broj ispitanika jest N=133. Podatci su bili prikupljeni
putem Bolničkog informacijskog sustava te arhive bolesnika.
Rezultati: Analizom podataka kroz proučavano razdoblje dobiveno je da od MRSA
oboljevaju bolesnici prosječne dobi od 77 godina, a udio žena iznosi N=72, (54,1%).
Odjeli pulmologije i gastroenterologije zabilježili su najviše MRSA bolesnika N=31,
(23,3%). Po završetku bolničkog liječenja, koje je u prosjeku trajalo 12 dana, najviše
bolesnika je smješteno u domove za starije i nemoćne N=62, (46,6%).
Zaključak: Rezultati istraživanja pokazuju kako kretanje MRSA u Općoj bolnici
Zabok i bolnici hrvatskih veterana biježi porast svake proučavane godine, dok se
zadnje, 2019. godine, broj pozitivnih MRSA bolesnika u prosjeku smanjio.

Abstract (english)

Introduction: Increased production of medicaments, accompanied with non-rational
use of medicaments, especially increased antibiotics use, has led to bacteria
modification so they cause certain clinical characteristics (illnesses) that led to
hospital-acquired infections. In the Republic of Croatia the most common infection is
caused by Staphylococus aureus virus, called Staphylococcus aureus that is metilicin
resistant (MRSA) being resistant to all common antibiotics. MRSA causes prolonged
hospitalization, imposes a risk of transmission among health care personal in hospital
and imposes financial burden to health care system. This paper reviews MRSA
prevalence in the General Hospital Zabok and Croatian Veterans' hospital in the
period 2015-2019 along with presentation of MRSA patients’ common characteristics.
Methodology: Study of characteristics of patients infected and colonized with MRSA
bacteria has been made by retrospective study of patients hospitalized in the General
Hospital Zabok and Croatian Veterans' hospital from January 1 2015 to December 31
2019; sample consists of 133 patients (N=133). Data were collected in Hospital’s
information system and patients data archive.
Results: Data analysis has shown that the average age of MRSA infected patients is
77 years; female patients percentage is 54,1%, (N=72). Pulmonology and
gastroenterology wards record the most MRSA patients 23,3%, (N=31). After
hospitalization, lasting at average 12 days, most of patients, 46,6%, were housed in
senior nursing facilities (N=62).
Conclusion: Study results have shown that MRSA prevalence in General Hospital
Zabok and Croatian Veterans' hospital was increasing during the studied years;
although, in the last year, 2019, the total of MRSA patients was decreased.

• Keywords: nfekcija; kolonizacija; meticilin rezistentni Staphylococcus aureus; Staphylococcus aureus; bolesnik
• Keywords (english): infection; colonization; meticilin resistant Staphylococcus aureus; Staphylococcus aureus; patient
• Language: croatian
• URN:NBN: urn:nbn:hr:105:029014
• Study programme: Title: Studies in Nursing; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-05-17 09:09:34