Extraintestinal manifestations of inflammatory bowel disease in children

master's thesis

• Author: Carolina Frances Koletić
• Mentor: Irena Senečić-Čala (mentor)
• Committee member: Duška Tješić-Drinković (predsjednik povjerenstva)
• Committee member: Marija Jelušić (član povjerenstva)
• Committee member: Irena Senečić-Čala (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Pediatrics); Zagreb
• Defense date and country: 2014-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Pediatrics

Abstract

Children with inflammatory bowel disease (IBD) have higher rates of extraintestinal manifestations (EIMs) than the adult IBD population.1 It is believed that these manifestations are an extension of the autoimmune inflammatory pathology of IBD into organs of the body outside of the gastrointestinal system such as musculoskeletal, hepatobiliary, oral, dermatological, and ophthalmological systems. Secondary EIMs are systemic changes that result from inflammation of the gastrointestinal system. These include, weight loss and growth failure, anemia, and decrease in bone mineral density. EIMs can present before, during, or after gastrointestinal symptoms and may not necessarily be congruous with the severity of IBD flares. The goal of this review is to inform clinicians about the relationship between various EIMs and IBD in order to expedite diagnosis and treatment of IBD and its complications. This is especially important in the pediatric population where a delay in diagnosis affects patients’ development and future health.

• Keywords: extraintestinal manifestation; inflammatory bowel disease; pediatrics
• Language: english
• URN:NBN: urn:nbn:hr:105:737579
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2015-11-20 09:41:55