prikaz prve stranice dokumenta Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice
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Scientific paper - Case study
Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice
European Heart Journal - Case Reports, 5 (2021), 2; ytab018. https://doi.org/10.1093/ehjcr/ytab018
Lakušić, Nenad; Sopek Merkaš, Ivana; Lučinger, Daren; Mahović, Darija

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Lakušić, N., Sopek Merkaš, I., Lučinger, D. & Mahović, D. (2021). Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice. European Heart Journal - Case Reports, 5. (2). doi: 10.1093/ehjcr/ytab018

Lakušić, Nenad, et al. "Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice." European Heart Journal - Case Reports, vol. 5, no. 2, 2021. https://doi.org/10.1093/ehjcr/ytab018

Lakušić, Nenad, Ivana Sopek Merkaš, Daren Lučinger and Darija Mahović. "Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice." European Heart Journal - Case Reports 5, no. 2 (2021). https://doi.org/10.1093/ehjcr/ytab018

Lakušić, N., et al. (2021) 'Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice', European Heart Journal - Case Reports, 5(2). doi: 10.1093/ehjcr/ytab018

Lakušić N, Sopek Merkaš I, Lučinger D, Mahović D. Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice. European Heart Journal - Case Reports [Internet]. 2021 February 01 [cited 2024 April 18];5(2). doi: 10.1093/ehjcr/ytab018

N. Lakušić, I. Sopek Merkaš, D. Lučinger and D. Mahović, "Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice", European Heart Journal - Case Reports, vol. 5, no. 2, February 2021. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:044878. [Accessed: 18 April 2024]

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Metadata
Title (english)Heterophile antibodies, false-positive troponin, and acute coronary syndrome: a case report indicating a pitfall in clinical practice
AuthorNenad Lakušić
AuthorIvana Sopek Merkaš
AuthorDaren Lučinger
AuthorDarija Mahović
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Neurology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Neurology
Abstract (english)
Background: Heterophile antibodies are one of the most common causes of false-positive troponin. ----- Case summary: We report a case of a 53-year-old woman with false-positive troponin elevation and a clinical presentation understood and treated as non-ST-elevation acute coronary syndrome. Because of chronic basal elevation of troponin (at a 'plateau' level) and chest pain, the patient underwent several invasive coronary angiograms until false-positive increase of troponin due to heterophile antibodies was suspected. Borderline stenosis of a left circumflex coronary artery found on first coronary angiogram was a coincidental finding and heterophile antibodies in the patient's serum were confirmed. ----- Discussion: This interesting case report aims to remind the clinicians about the possibility of false-positive troponin level due to laboratory analytical interference caused by heterophile antibodies. In this case, it is important to suspect false-positive troponin elevation, even when coronary artery disease is found. This rare and less mentioned and/or recognized cause of troponin elevation may lead to unnecessary invasive diagnostics and aggressive treatment of patients.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleEuropean Heart Journal - Case Reports
Numberingvol. 5, no. 2, ytab018
e-ISSN2514-2119
DOIhttps://doi.org/10.1093/ehjcr/ytab018
URN:NBNurn:nbn:hr:105:044878
Publication2021-02-01
Document URLhttps://academic.oup.com/ehjcr/article/doi/10.1093/ehjcr/ytab018/6127629
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial 4.0 International (CC BY-NC 4.0) icon
Created on2021-07-01 08:29:53