prikaz prve stranice dokumenta Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
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Scientific paper - Review paper
Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
Reumatologia/Rheumatology, 58 (2020), 6; 390-400. https://doi.org/10.5114/reum.2020.101400
Padjen, Ivan; Reihl Crnogaj, Mirna; Anić, Branimir

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Padjen, I., Reihl Crnogaj, M. & Anić, B. (2020). Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms. Reumatologia/Rheumatology, 58. (6), 390-400. doi: 10.5114/reum.2020.101400

Padjen, Ivan, et al. "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms." Reumatologia/Rheumatology, vol. 58, no. 6, 2020, pp. 390-400. https://doi.org/10.5114/reum.2020.101400

Padjen, Ivan, Mirna Reihl Crnogaj and Branimir Anić. "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms." Reumatologia/Rheumatology 58, no. 6 (2020): 390-400. https://doi.org/10.5114/reum.2020.101400

Padjen, I., Reihl Crnogaj, M. and Anić, B. (2020) 'Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms', Reumatologia/Rheumatology, 58(6), pp. 390-400. doi: 10.5114/reum.2020.101400

Padjen I, Reihl Crnogaj M, Anić B. Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms. Reumatologia/Rheumatology [Internet]. 2020 [cited 2024 November 17];58(6):390-400. doi: 10.5114/reum.2020.101400

I. Padjen, M. Reihl Crnogaj and B. Anić, "Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms", Reumatologia/Rheumatology, vol. 58, no. 6, pp. 390-400, 2020. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:515748. [Accessed: 17 November 2024]

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Metadata
Title (english)Conventional disease-modifying agents in rheumatoid arthritis – a review of their current use and role in treatment algorithms
AuthorIvan Padjen
AuthorMirna Reihl Crnogaj
AuthorBranimir Anić
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Internal Medicine)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Internal Medicine
Abstract (english)
Despite the development of targeted therapies, conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) remain the cornerstone of treatment of rheumatoid arthritis (RA). A literature search was conducted on treatment recommendations and relevant papers regarding new insights on therapeutics in rheumatoid arthritis. Methotrexate is considered the "anchor drug" due to its high efficacy as monotherapy and in combination with other conventional and targeted agents. Leflunomide and sulfasalazine are sound alternatives, whereas (hydroxy)chloroquine is primarily used in combination with other csDMARDs. Their use is encouraged in all treatment phases - in combination with targeted agents, and with other csDMARDs. Combining different csDMARDs is especially attractive in lower income settings given the evidence proving (almost) equal efficacy and safety of the csDMARD combination approach compared to the combination of targeted agents with a csDMARD. The aim of this review is to provide a clinically oriented insight into the pharmacology of each csDMARD and their place in treatment algorithms.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleReumatologia/Rheumatology
Numberingvol. 58, no. 6, pp. 390-400
p-ISSN0034-6233
e-ISSN2084-9834
DOIhttps://doi.org/10.5114/reum.2020.101400
URN:NBNurn:nbn:hr:105:515748
Publication2020
Document URLhttps://www.termedia.pl/doi/10.5114/reum.2020.101400
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) icon
Created on2021-07-06 11:42:46