Istraživanje rinosinusnih simptoma u kirurški liječenih bolesnika s kroničnim rinosinuitisom

master's thesis

• Title (english): Research of sinonasal symptoms in patients who underwent surgery for chronic rhinosinusitis
• Author: Ana Marija Kuća
• Mentor: Tomislav Baudoin (mentor)
• Committee member: Livije Kalogjera (predsjednik povjerenstva)
• Committee member: Mihael Ries (član povjerenstva)
• Committee member: Tomislav Baudoin (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Othorhinolaryngology and Head and Neck Surgery); Zagreb
• Defense date and country: 2020-07-17, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Otorhinolaryngology

Abstract

Kronični rinosinuitis je upalna bolest koja zahvaća sluznicu nosa i paranazalnih sinusa. Čest je zdravtsveni problem sa širokim rasponom simptoma i značajnim utjecajem na kvalitetu života oboljelih. Prema EPOS-ovim smjernicama klinička dijagnoza kroničnog rinosinuitisa postavlja se ako su u trajanju dužem od 12 tjedana prisutna dva ili više simptoma od kojih jedan mora biti nosna opstrukcija ili nosna sekrecija uz moguće simptome pritiska/boli u području lica ili poremećaja osjeta njuha. U ovom istraživanju proučavani su prijeoperativni rinosinusni simptomi u bolesnika s dijagnozom kroničnog rinosinuitisa koji su liječeni kirurški na Klinici za otorinolaringologiju i kirurgiju glave i vrata Kliničkog bolničkog centra „Sestre Milosrdnice“ tijekom 2018. godine. Podaci korišteni u istraživanju prikupljeni su iz medicinske dokumentacije ispitanika. U istraživanje je uključeno 70 ispitanika, od kojih je 37 žena i 33 muškaraca. Raspon dobi ispitanika bio je od 11 do 70 godina s medijanom dobi od 41 godine. U obzir je uzeto prisustvo/odusutstvo jedanaest rinosinusnih simptoma. Prikazana je općenita distribucija simptoma u ispitanika, distribucija simptoma s obzirom na spol ispitanika, distribucija simptoma s obzirom na pridružene bolesti i distribucija simptoma s obzirom na operacije. Rezultati su pokazali da je učestalost kardinalnih simptoma KRS-a znatno veća u odnosu na druge promatrane rinosinusne simptome. Tri najučestalija rinosinusna simptoma su nosna opstrukcija, postnazalni drip i pritisak/bol u području lica. S obzirom na pridružene bolesti, između promatranih skupina uočena je statistički značajna razlika u učestalosti nosne opstrukcije, postnazalnog dripa i pritiska/boli u području lica. S obzirom na vrstu operacije, između promatranih skupina uočena je statistički značajna razlika u učestalosti nosne opstrukcije, sekrecije na nos, hiposmije i anosmije.

Abstract (english)

Chronic rhinosinusitis is an inflammatory disease of the nose and paransal sinuses. It is common health problem with wide range of symptoms and with significant impact on the quality of life in people suffering from the illness. According to the EPOS criteria chronic rhinosinusitis is diagnosed based on the following criteria: 2 or more symptoms present in duration of 12 or more weeks, one of which has to be nasal obstruction or nasal secretion, with or without associated symptoms of facial pain/pressure and disorted sense of smell. This study assessed the preoperative sinonasal symptoms in patients with chronic rhinosinusitis who underwent surgery for chronic rhinosinusitis at the Department of Otorhynolaryngology, Head and Neck Surgery at Sisters of Charity University Hospital during a year period of 2018. Information about examinees was provided by hospital's medical documentation. Research included 70 patients altogether, 37 female and 33 male, respectfully. Age range varied between 11 to 70 years of age, with the median age being 41. Presence of eleven sinonasal symptoms or lack thereof is taken in consideration. In this research the common distribution of symptoms, distribution of symptoms in accordance with patient's associated diseases, as well as, symptom distribution in accordance with surgical operation performed is presented. According to results, the frequency of cardinal symptoms of chronic rhinosinusitis is significantly higher in comparison to other sinonasal symptoms. Three most common symptoms of rhinosinuitis observed in this population are nasal obstruction, postnasal drip and facila pain/pressure. In consideration to associated diseases found in observed population a stattistically remarkable difference between observed groups is found regarding following symptoms: nasal obstruction, postnasal drip and facial pain/pressure. In consideration to the type of surgical intervention performed a stattistically remarkable difference between groups is found regarding following symptoms: nasal obstruction, rhinorrhea, hyposmia and anosmia.

• Keywords: kronični rinosinuitis (KRS); rinosinusni simptomi
• Keywords (english): chronic rhinosinusitis; sinonasal symptoms
• Language: croatian
• URN:NBN: urn:nbn:hr:105:094151
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2021-09-13 08:18:54