Primjena kemijskog pilinga u uklanjanju znakova starenja kože

master's thesis

• Title (english): The use of chemical peel in removing signs of skin aging
• Author: Ana Franić
• Mentor: Zrinka Bukvić Mokos (mentor)
• Committee member: Branka Marinović (predsjednik povjerenstva)
• Committee member: Romana Čeović (član povjerenstva)
• Committee member: Zrinka Bukvić Mokos (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Dermatology); Zagreb
• Defense date and country: 2021-07-16, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Dermatovenerology

Abstract

Starenje kože progresivan je proces koji započinje u trećem desetljeću života, a čine ga intrinzičko i ekstrinzičko starenje. Intrinzičko je starenje neizbježno, a pridonose mu slobodni kisikovi radikali, skraćivanje telomera i smanjena sinteza spolnih hormona. Ekstrinzičko starenje smatra se starenjem pod utjecajem okolišnih čimbenika, pri čemu je najznačajniji čimbenik izloženost ultraljubičastom (UV) zračenju, tzv. fotostarenje. Kemijski je piling metoda koja se često rabi, a uključuje primjenu kemijskih supstancija s ciljem eksfolijacije pojedinih slojeva kože. Ova metoda koristi se već godinama kod pomlađivanja kože sa svrhom djelovanja na površinske i duboke bore te dispigmentacije, a dovodi i do poboljšanja teksture i tonusa kože. Razlikuju se vrlo površinski, površinski, srednje duboki i duboki kemijski piling. Kemijske supstancije korištene za kemijski piling uključuju primjenu različitih kiselina (glikolna kiselina, mliječna kiselina, salicilna kiselina, trikloroctena kiselina) te primjenu fenola i njegovih derivata. Nakon primjene kemijskog pilinga dolazi do eksfolijacije pojedinih slojeva kože i njezinog pomlađivanja stimulacijom sinteze kolagena i elastičnih vlakana. Uspješnost kemijskog pilinga ovisit će o odabiru pacijenta, upotrijebljenoj kemijskoj supstanciji i njezinoj koncentraciji, načinu primjene i pripremi za kemijski piling. Nakon primjene kemijskog pilinga, koža zahijeva odgovarajuću njegu kako bi se osigurao pravovremeni oporavak i spriječili neželjeni učinci.

Abstract (english)

Skin aging is a progressive process with the onset at the third decade of life, consisting of intrinsic and extrinsic aging. Reactive oxygen species, telomere shortening, and reduced synthesis of sex hormones contribute to intrinsic aging which is inevitable. Extrinsic aging is aging under the influence of environmental factors and the major factor for its development is ultraviolet (UV) radiation, the so-called photoaging. Chemical peeling is a common method that involves the application of chemical substances leading to exfoliation of individual layers of the skin. This method has been used for years for skin rejuvenation using for fine lines, deep wrinkles and dyspigmentation; additionally, it improves the texture and tone of the skin. Facial peels are divided into very superficial, superficial, medium and deep chemical peel. Chemical agents used for chemical peels include various acids (glycolic acid, lactic acid, salicylic acid, trichloroacetic acid) and phenol and its derivatives. After chemical peeling, individual layers of the skin exfoliate and rejuvenate through the stimulation of synthesis of collagen and elastic fibers. Chemical peel efficiency depends on patient selection, chemical agent and its concentration and on preparation and application of chemical peel. After applying a chemical peel, the skin requires proper care to ensure timely recovery and prevent side effects.

• Keywords: kemijski piling; starenje kože; fotostarenje
• Keywords (english): chemical peel; skin aging; photoaging
• Language: croatian
• URN:NBN: urn:nbn:hr:105:094699
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2022-02-03 10:16:26