Primary and secondary hepatic lymphomas diagnosed by image-guided fine-needle aspiration

master's thesis

• Title: Primary and secondary hepatic lymphomas diagnosed by image-guided fine-needle aspiration : a retrospective study of clincal and cytomorphologic findings
• Author: Matea Deliu
• Mentor: SVEN SEIWERTH (mentor)
• Committee member: Marijana Ćorić (predsjednik povjerenstva)
• Committee member: Slavko Gašparov (član povjerenstva)
• Committee member: SVEN SEIWERTH (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2014-07-15, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Pathology

Abstract

Objectives: To explore the diagnosis of hematolymphoid
malignancies of the liver (hepatic lymphoma [HeL]) by
image-guided fine-needle aspiration (FNA), which can often
be difficult due to a low index of suspicion and nonspecific
patient presentations, especially in the rare cases where
the liver is the only site of disease (primary HeL [PHeL]).
Understanding the clinical setting in which such lesions
arise, as well as the cytomorphologic findings, may assist
cytopathologists in making an accurate diagnosis and
triaging samples for ancillary studies.----- Methods: In this retrospective study of 32 patients with
HeL, the largest such study to our knowledge, we review the
clinical and diagnostic features of HeL.----- Results: HeL and especially PHeL most commonly show
a diffuse large B-cell lymphoma phenotype and have a
poor prognosis (median survival of seven months). PHeL
is strongly associated with human immunodeficiency virus
infection (12/16 patients).----- Conclusions: Image-guided FNA with immediate evaluation
is a reliable means to obtain diagnostic material and triage
for ancillary tests.

• Keywords: hepatic; liver; lymphoma; hematolymphoid; fine-needle aspiration; HIV; primary cytology
• Language: english
• URN:NBN: urn:nbn:hr:105:884414
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Access restricted to students and staff of home institution
• Created on: 2015-12-15 12:46:27