| Abstract | Arterijska hipertenzija i dislipidemija su glavni rizični čimbenici za razvoj kardiovaskularnih bolesti koje je moguće uspješno prevenirati i liječiti. Prevalencija hipertenzije je viša u muškaraca nego u premenopauzalnih žena iste dobi, dok je situacija obrnuta u starijoj dobi gdje je prevalencija hipertenzije viša u postmenopauzalnih žena nego u muškaraca iste dobi. Prevalencija dislipidemije je viša u žena nego u muškaraca. U našem istraživanju prikupili smo podatke o bolesnicima koji su tijekom 2016. godine primljeni na Kliniku za bolesti srca i krvnih žila Kliničkog bolničkog centra Sestre milosrdnice s dijagnozom akutnog koronarnog sindroma te usporedili razlike između muškaraca i žena u liječenju hipertenzije i dislipidemije. Ukupno je 501 bolesnik sudjelovao u istraživanju, od čega je bilo 327 muškaraca i 174 žene. Hipertenzija je bila prisutna kod 86,8% žena i 74,6% muškaraca (p=0,002). Dislipidemija je bila prisutna kod 47,1% žena i 46,2% muškaraca (p=0,84). 46,6% žena koristilo je ACEi/ARB-ove u terapiji hipertenzije, dok je iste lijekove koristilo 41,6% muškaraca (p=0,286). Beta-blokatore u terapiji hipertenzije koristilo je 34,5% žena i 26,6% muškaraca (p=0,065). U terapiji dislipidemije, statine je koristilo 17,8% žena i 15% muškaraca (p=0,41). Kao što možemo vidjeti, jedino je razlika u prevalenciji hipertenzije statistički značajna, dok razlike u prevalenciji dislipidemije, liječenju hipertenzije i dislipidemije nisu statistički značajne. Farmakoterapijskih razlika između muškaraca i žena nije bilo. Zaključno možemo reći da, iako naše istraživanje na malom uzorku nije pokazalo značajnih razlika, potrebna su daljnja istraživanja kako bi se razjasnile razlike u kardiovaskularnom mortalitetu između muškaraca i žena. |
| Abstract (english) | Arterial hypertension and dyslipidemia are the main treatable risk factors for developing cardiovascular diseases. Prevalence of hypertension is higher in men than in age-matching premenopausal women, whereas hypertension is more common in postmenopausal women than in age-matching men. Prevalence of dyslipidemia is higher in women than in men. In this study we collected data from patients admitted to the Clinic for Cardiovascular Diseases of KBC Sestre milosrdnice with a diagnose of acute coronary syndrome in 2016 and compared the differences in treatment of hypertension and dyslipidemia between men and women. A total of 501 patient (327 men and 174 women) participated in the study. Hypertension was present in 86.8% of women and in 74.6% of men (p=0.002). Dyslipidemia was present in 47.1% of women and in 46.2% of men (p=0.84). 46.6 % of women were using ACEi/ARB medications in the treatment of hypertension, whereas 41.6% of men were using this medications (p=0.286). 34.5% of women were using beta-blockers, medications also used in the treatment of hypertension, whereas 26.6% of men were using this medications (p=0.065). 17.8% of women were using statins, medication used for the treatment of dyslipidemia, whereas 15% of men were using this medication (p=0.41). As we can see, only the difference in the prevalence of hypertension is statistically significant, while the difference in the prevalence of dyslipidemia is not statistically significant. There were no significant differences in drugs used to treat hypertension or dyslipidemia. In conclusion, we should point out that our study had a very limited number of patients and further larger studies are needed to properly evaluate this topic. |
