Utjecaj razine kolesterola na psihopatološke fenomene

master's thesis

• Title (english): The effect of cholesterol level on psychopathology
• Author: Nikoleta Marlais
• Mentor: Aleksandar Savić (mentor)
• Committee member: Neven Henigsberg (predsjednik povjerenstva)
• Committee member: Dražen Begić (član povjerenstva)
• Committee member: Aleksandar Savić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Psychiatry and Psychological Medicine); Zagreb
• Defense date and country: 2022-09-20, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Psychiatry

Abstract

CILJ: Ispitati utjecaj razine kolesterola na psihopatološke fenomene kod ispitanika vještačenih u Zavodu za forenzičku psihijatriju „Dr. Vlado Jukić“, Klinike za psihijatriju Vrapče s podacima prikupljenima iz psihijatrijskih vještačenja učinjenih u periodu od 1. siječnja 2012. do 31. prosinca 2021. godine. -----
ISPITANICI I METODE: Retrospektivno prikupljeni podaci ispitanika kojima je zbog obilježja počinjenja kaznenih djela sudskim putem bilo određeno provođenje forenzičkog vještačenja. U... More ispitivanje su uključeni ispitanici kojima je u laboratorijskoj obradi određivana ukupna vrijednost kolesterola u serumu. Prikupljeni su podaci o povijesti psihijatrijskih i sustavnih bolesti, rezultati psihologijskog testiranja (promatrani parametri bili su: impulzivnost, nizak prag tolerancije na frustraciju, agresivnost i emocionalna nestabilnost), vrsta kaznenog djela te vrijednosti kolesterola. -----
REZULTATI: U istraživanju su obrađeni podaci od 586 ispitanika iz forenzičko-psihijatrijske populacije, te su analizirani podaci 190 ispitanika koji su imali vrijednosti kolesterola u laboratorijskoj obradi. Medijan dobi iznosio je 40,57 godina s rasponom od 17 do 76 godina. Bilo je 164 muškaraca (86,3 %) i 26 žena (13,7 %), od kojih je 82,6 % počinilo nasilna kaznena djela. Pronađene su statistički značajno niže vrijednosti kolesterola kod ispitanika sa zabilježenom impulzivnošću u psihologijskom testiranju (p=0,041) u skupini ispitanika koji nemaju zabilježen organitet i/ili psihozu. -----
ZAKLJUČAK: U istraživanju su registrirani trendovi nižih vrijednosti kolesterola kod ispitanika u svim pojedinačno promatranim parametrima te u skupini ispitanika s poremećajima ličnosti. Dobiven je statistički značajan rezultat u jednoj skupini ispitanika sa zabilježenom impulzivnošću. U daljnjim istraživanjima potrebno je napraviti prospektivnu studiju s većim brojem ispitanika kako bismo bolje utvrdili međuodnos kolesterola i promatranih varijabli. Less

Abstract (english)

OBJECTIVES: To examine the influence of cholesterol levels on psychopathological phenomena in individuals based on psychiatric evaluations conducted at the Department of Forensic Psychiatry "Dr. Vlado Jukić", University Psychiatric Hospital Vrapče with data collected from psychiatric expert examinations performed from January 1, 2012 to December 31, 2021. -----
PARTICIPANTS AND METHODS: All data was restrospectively collected from respondents who had undergone court-ordered forensic expert... More examinations on account of their crimes. Subjects who had serum cholesterol levels in their case files were included in our study. Data was collected about psychiatric and systemic diseases, psychological testing results (parameters assessed were: impulsivity, aggression, emotional instability, low tolerance to frustration), nature of the crime, and cholesterol values. -----
RESULTS: Data for 586 subjects from the forensic psychiatric population was extracted and analysed, of which 190 subjects had data on cholesterol levels. The median age of subjects was 40.57 years, with a range of 17 to 76 years. There were 164 men (86,3%) and 26 women (13,7%), and of our 190 subjects, 82.6% had commited a violent crime. Statistically significant lower cholesterol values were observed for subjects who were deemed impulsive in psychological testing (p=0,041) in subjects who had no organic brain diseases and/or psychosis. -----
CONCLUSION: In our study, a trend of lower cholesterol values was observed in all subjects in all observed parameters, as well as in subjects with personality disorders. We observed statistically relevant results in one group of subjects with recorded impulsivity. In further studies, a prospective study with a larger sample size should be considered to elucidate the relationship between cholesterol and observed variables. Less

• Keywords: kolesterol; agresivnost; impulzivnost
• Keywords (english): cholesterol; aggression; impulsivity
• Language: croatian
• URN:NBN: urn:nbn:hr:105:334327
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-01-19 08:47:58