prikaz prve stranice dokumenta Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians
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Scientific paper - Original scientific paper
Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians
PLOS ONE, 17 (2022), 12; e0275336. https://doi.org/10.1371/journal.pone.0275336
Dewez, Juan Emmanuel; Pembrey, Lucy; Nijman, Ruud G.; del Torso, Stefano; Grossman, Zachi; Hadjipanayis, Adamos; Van Esso, Diego; Lim, Emma; Emonts, Marieke; Burns, James; Gras-LeGuen, Christèle; Kohlfuerst, Daniela; Dornbusch, Hans Jürgen; Brengel-Pesce, Karen; Mallet, Francois; von Both, Ulrich; Tsolia, Maria; Eleftheriou, Irini; Zavadska, Dace; de Groot, Ronald; van der Flier, Michiel; Moll, Henriëtte; Hagedoorn, Nienke; Borensztajn, Dorine; Oostenbrink, Rianne; Kuijpers, Taco; Pokorn, Marko; Vincek, Katarina; Martinón-Torres, Federico; Rivero, Irene; Agyeman, Philipp; Carrol, Enitan D.; Paulus, Stéphane; Cunnington, Aubrey; Herberg, Jethro; Levin, Michael; Mujkić, Aida; Geitmann, Karin; Da Dalt, Liviana; Valiulis, Arūnas; Lapatto, Risto; Syridou, Garyfallia; Altorjai, Péter; Torpiano, Paul; Størdal, Ketil; Illy, Károly; Mazur, Artur; Spreitzer, Mateja Vintar; Rios, Joana; Wyder, Corinne; Romankevych, Ivanna; Basmaci, Romain; Ibanez-Mico, Salvador; Yeung, Shunmay More authors...

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Dewez, J. E., Pembrey, L., Nijman, R. G., del Torso, S., Grossman, Z., Hadjipanayis, A. ... Yeung, S. (2022). Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians. PLOS ONE, 17. (12). doi: 10.1371/journal.pone.0275336

Dewez, Juan Emmanuel, et al. "Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians." PLOS ONE, vol. 17, no. 12, 2022. https://doi.org/10.1371/journal.pone.0275336

Dewez, Juan Emmanuel, Lucy Pembrey, Ruud G. Nijman, Stefano del Torso, Zachi Grossman, Adamos Hadjipanayis, Diego Van Esso, et al. "Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians." PLOS ONE 17, no. 12 (2022). https://doi.org/10.1371/journal.pone.0275336

Dewez, J. E., et al. (2022) 'Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians', PLOS ONE, 17(12). doi: 10.1371/journal.pone.0275336

Dewez JE, Pembrey L, Nijman RG, del Torso S, Grossman Z, Hadjipanayis A, and sur.. Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians. PLOS ONE [Internet]. 2022 December 20 [cited 2025 April 26];17(12). doi: 10.1371/journal.pone.0275336

J. E. Dewez, et al., "Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians", PLOS ONE, vol. 17, no. 12, December 2022. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:580073. [Accessed: 26 April 2025]

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Title (english)Availability and use of rapid diagnostic tests for the management of acute childhood infections in Europe: A cross-sectional survey of paediatricians
AuthorJuan Emmanuel Dewez
AuthorLucy Pembrey
AuthorRuud G. Nijman
AuthorStefano del Torso
AuthorZachi Grossman
AuthorAdamos Hadjipanayis
AuthorDiego Van Esso
AuthorEmma Lim
AuthorMarieke Emonts
AuthorJames Burns
AuthorChristèle Gras-LeGuen
AuthorDaniela Kohlfuerst
AuthorHans Jürgen Dornbusch
AuthorKaren Brengel-Pesce
AuthorFrancois Mallet
AuthorUlrich von Both
AuthorMaria Tsolia
AuthorIrini Eleftheriou
AuthorDace Zavadska
AuthorRonald de Groot
AuthorMichiel van der Flier
AuthorHenriëtte Moll
AuthorNienke Hagedoorn
AuthorDorine Borensztajn
AuthorRianne Oostenbrink
AuthorTaco Kuijpers
AuthorMarko Pokorn
AuthorKatarina Vincek
AuthorFederico Martinón-Torres
AuthorIrene Rivero
AuthorPhilipp Agyeman
AuthorEnitan D. Carrol
AuthorStéphane Paulus
AuthorAubrey Cunnington
AuthorJethro Herberg
AuthorMichael Levin
AuthorAida Mujkić
AuthorKarin Geitmann
AuthorLiviana Da Dalt
AuthorArūnas Valiulis
AuthorRisto Lapatto
AuthorGaryfallia Syridou
AuthorPéter Altorjai
AuthorPaul Torpiano
AuthorKetil Størdal
AuthorKároly Illy
AuthorArtur Mazur
AuthorMateja Vintar Spreitzer
AuthorJoana Rios
AuthorCorinne Wyder
AuthorIvanna Romankevych
AuthorRomain Basmaci
AuthorSalvador Ibanez-Mico
AuthorShunmay Yeung
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Social Medicine and Health Care Organization)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Public Health and Health Care
Social Medicine
Abstract (english)
Background: Point-of-care-tests (POCTs) have been advocated to optimise care in patients with infections but their actual use varies. This study aimed to estimate the variability in the adoption of current POCTs by paediatricians across Europe, and to explore the determinants of variability. Methods and findings: A cross-sectional survey was conducted of hospital and primary care paediatricians, recruited through professional networks. Questions focused on the availability and use of currently available POCTs. Data were analysed descriptively and using Median Odds Ratio (MOR) to measure variation between countries. Multilevel regression modelling using changes in the area under the receiver operating characteristic curve of models were used to assess the contribution of individual or workplace versus country level factors, to the observed variation. The commonest POCT was urine dipsticks (UD) which were available to >80% of primary care and hospital paediatricians in 68% (13/19) and 79% (23/29) countries, respectively. Availability of all POCTs varied between countries. In primary care, the country (MOR) varied from 1.61 (95%CI: 1.04-2.58) for lactate to 7.28 (95%CI: 3.04-24.35) for UD. In hospitals, the country MOR varied from 1.37 (95%CI:1.04-1.80) for lactate to 11.93 (95%CI:3.35-72.23) for UD. Most paediatricians in primary care (69%, 795/1154) and hospital (81%, 962/1188) would use a diagnostic test in the case scenario of an infant with undifferentiated fever. Multilevel regression modelling showed that the country of work was more important in predicting both the availability and use of POCTs than individual or workplace characteristics. Conclusion: There is substantial variability in the adoption of POCTs for the management of acute infections in children across Europe. To inform future implementation of both existing and innovative tests, further research is needed to understand what drives the variation between countries, the needs of frontline clinicians, and the role of diagnostic tests in the management of acute childhood infections.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titlePLOS ONE
Numberingvol. 17, no. 12, e0275336
e-ISSN1932-6203
DOIhttps://doi.org/10.1371/journal.pone.0275336
URN:NBNurn:nbn:hr:105:580073
Publication2022-12-20
Document URLhttps://dx.plos.org/10.1371/journal.pone.0275336
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2023-05-16 07:55:17