Vrste transplantata prednjeg križnog ligamenta

master's thesis

• Title (english): Types od anterior cruciate ligament grafts
• Author: Ivo Bastić
• Mentor: Mislav Jelić (mentor)
• Committee member: Ivan Bohaček (predsjednik povjerenstva)
• Committee member: Tomislav Đapić (član povjerenstva)
• Committee member: Mislav Jelić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Orthopedics); Zagreb
• Defense date and country: 2023-07-13, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Orthopedics

Abstract

Ozljede prednjeg križnog ligamenta su najčešće ozljede ligamenata koljena. Prednja ukrižena sveza je iznimno važna zbog svoje presudne uloge u održavanju stabilnosti koljena. Zbog nemogućnosti prednjeg križnog ligamenta da sam zacijeli, u slučaju ozljede ligamenta pristupa se njegovoj rekonstrukciji koristeći transplantate, kako bi se ostvarila ponovna uspostava prirodnih anatomskih i funkcionalnih odnosa u koljenu. Tijekom povijesti razvijale su se sve bolje i naprednije tehnike, te otkrivali novi načini kirurškog liječenja, s ciljem pronalaska najoptimalnije zamjene za nativni prednji križni ligament. Za sada, najučinkovitijima su se pokazali transplantati od vlastitog tkiva pacijenta, tzv. autologni transplantati. Uz njih, za liječenje ozljeda prednjeg križnog ligamenta na raspolaganju su i alogeni transplantati, odnosno tkiva koja su pribavljena od humanih kadavera i pohranjena u banke tkiva. Sintetički transplantati se u prošlosti nisu dokazali kao pouzdana opcija, ali napredovanjem tehnologije i otkrivanjem novih materijala, ova vrsta transplantata ponovno privlači sve veći interes te ima veliki potencijal u budućnosti rekonstrukcije ACL-a.

Abstract (english)

Anterior cruciate ligament (ACL) injuries are the most common knee ligament injuries. The ACL is an extremely important ligament because of its crucial role in maintaining knee stability. Due to the inability of the anterior cruciate ligament to heal on its own, in case of injury to the ligament, its reconstruction is approached using grafts in order to achieve the re-establishment of natural anatomical and functional relationships in the knee. Throughout history, better and more advanced techniques have been developed, and new methods of surgical treatment have been discovered, with the aim of finding the most optimal replacement for the native anterior cruciate ligament. For now, transplants from the patient's own tissue, the so-called autografts, have proven to be the most effective. In addition to them, allogeneic transplants, i.e. tissues obtained from human cadavers and stored in tissue banks, are also available for the treatment of anterior cruciate ligament injuries. Synthetic grafts have not been proven as a reliable option in the past, but with the advancement of technology and the discovery of new materials, this type of graft is once again attracting increasing interest and has great potential in the future of ACL reconstruction.

• Keywords: križni ligament; transplantat križnog ligamenta; koljeno
• Keywords (english): anterior cruciate ligament; anterior cruciate ligament grafts; knee
• Language: croatian
• URN:NBN: urn:nbn:hr:105:628695
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2023-10-20 10:50:44