Evaluation of the Photoactivation Effect of 3% Hydrogen Peroxide in the Disinfection of Dental Implants: In Vitro Study

Scientific paper - Original scientific paper

• Author: Ivan Katalinić; MBZ: 60653
• Author: Igor Smojver
• Author: Luka Morelato
• Author: Marko Vuletić
• Author: Ana Budimir
• Author: Dragana Gabrić
• Author's institution: University of Zagreb; School of Medicine; (Department of Medical Microbiology and Parasitology)
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Medical Microbiology

Abstract (english)

Photoactivation of 3% hydrogen peroxide with a 445 nm diode laser represents a relatively new, insufficiently researched antimicrobial method in the treatment of peri-implantitis. The purpose of this work is to evaluate the effect of photoactivation of 3% hydrogen peroxide with a 445 nm diode laser, and to compare the obtained results with 0.2% chlorhexidine treatment and 3% hydrogen peroxide treatment without photoactivation, in vitro, on the surface of dental implants contaminated with S. aureus and C. albicans biofilms. Previously, 80 infected titanium implants with S. aureus and C. albicans cultures were divided into four groups: G1-negative control (no treatment), G2-positive control (0.2% chlorhexidine), G3 (3% hydrogen peroxide), and G4 (photoactivated 3% hydrogen peroxide). The number of viable microbes in each sample was determined by the colony forming unit (CFU) count. The results were statistically processed and analyzed, showing a statistically significant difference across all groups compared to the negative control (G1), and the absence of a statistically significant difference between groups G1–G3. The new antimicrobial treatment, according to the results, could be worthy of further analysis and research.

• Keywords (english): 3% hydrogen peroxide; diode laser; periimplantitis therapy; photoactivation
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Biomedicines
• Numbering: vol. 11, no. 4, p. 1002, 1002
• e-ISSN: 2227-9059
• DOI: https://doi.org/10.3390/biomedicines11041002
• URN:NBN: urn:nbn:hr:105:648042
• Publication: 2023-03-24
• Document URL: https://www.mdpi.com/2227-9059/11/4/1002
• Type of resource: Text
• Access conditions: Open access
• Created on: 2023-10-27 08:48:07