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Scientific paper - Original scientific paper
Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study
Diagnostics, 13 (2023), 4; 694. https://doi.org/10.3390/diagnostics13040694
Kovačević, Lucija; Petrovečki, Marko; Korša, Lea; Marušić, Zlatko; Dumić-Čule, Ivo; Prutki, Maja

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Kovačević, L., Petrovečki, M., Korša, L., Marušić, Z., Dumić Čule, I. & Prutki, M. (2023). Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study. Diagnostics, 13. (4). doi: 10.3390/diagnostics13040694

Kovačević, Lucija, et al. "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study." Diagnostics, vol. 13, no. 4, 2023. https://doi.org/10.3390/diagnostics13040694

Kovačević, Lucija, Marko Petrovečki, Lea Korša, Zlatko Marušić, Ivo Dumić Čule and Maja Prutki. "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study." Diagnostics 13, no. 4 (2023). https://doi.org/10.3390/diagnostics13040694

Kovačević, L., et al. (2023) 'Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study', Diagnostics, 13(4). doi: 10.3390/diagnostics13040694

Kovačević L, Petrovečki M, Korša L, Marušić Z, Dumić Čule I, Prutki M. Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study. Diagnostics [Internet]. 2023 February 12 [cited 2024 December 07];13(4). doi: 10.3390/diagnostics13040694

L. Kovačević, M. Petrovečki, L. Korša, Z. Marušić, I. Dumić Čule and M. Prutki, "Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study", Diagnostics, vol. 13, no. 4, February 2023. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:816422. [Accessed: 07 December 2024]

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Metadata
Title (english)Early Assessment of Neoadjuvant Chemotherapy Response Using Multiparametric Magnetic Resonance Imaging in Luminal B-like Subtype of Breast Cancer Patients: A Single-Center Prospective Study
AuthorLucija Kovačević
AuthorMarko Petrovečki
AuthorLea Korša
AuthorZlatko Marušić
AuthorIvo Dumić-Čule
AuthorMaja Prutki
Author's institutionUniversity of Zagreb
School of Medicine
(Department of Radiology)
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Radiology
Abstract (english)
This study aimed to evaluate the performance of multiparametric breast magnetic resonance imaging (mpMRI) for predicting response to neoadjuvant chemotherapy (NAC) in patients with luminal B subtype breast cancer. The prospective study included thirty-five patients treated with NAC for both early and locally advanced breast cancer of the luminal B subtype at the University Hospital Centre Zagreb between January 2015 and December 2018. All patients underwent breast mpMRI before and after two cycles of NAC. Evaluation of mpMRI examinations included analysis of both morphological (shape, margins, and pattern of enhancement) and kinetic characteristics (initial signal increase and post-initial behavior of the time-signal intensity curve), which were additionally interpreted with a Göttingen score (GS). Histopathological analysis of surgical specimens included grading the tumor response based on the residual cancer burden (RCB) grading system and revealed 29 NAC responders (RCB-0 (pCR), I, II) and 6 NAC non-responders (RCB-III). Changes in GS were compared with RCB classes. A lack of GS decrease after the second cycle of NAC is associated with RCB class and non-responders to NAC.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleDiagnostics
Numberingvol. 13, no. 4, 694
e-ISSN2075-4418
DOIhttps://doi.org/10.3390/diagnostics13040694
URN:NBNurn:nbn:hr:105:816422
Publication2023-02-12
Document URLhttps://www.mdpi.com/2075-4418/13/4/694
Type of resourceText
Access conditionsOpen access
Terms of useLicence Attribution 4.0 International (CC BY 4.0) icon
Created on2024-01-15 08:27:45