Tear film status in glaucoma patients

Professional paper - Review paper

• Title (croatian): Stanje suznog filma glaukomskih pacijenata
• Author: Sonja Jandroković
• Author: Smiljka Popović Suić
• Author: Rajko Kordić
• Author: Tomislav Kuzman
• Author: Igor Petriček
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

The purpose of this study was to determine the prevalence of ocular surface disease symptoms and the state of the tear film among patients with glaucoma who are receiving topical intraocular pressure lowering monotherapy. 62 responders were divided in 2 groups: 32 glaucoma patients and 30 healthy individuals. Tear film break-up time (TBUT), Schirmer 1 testing and ocular surface disease questionnaire were performed in both groups. 50% glaucoma patients and 25% control group participants had dry eye symptoms. Advanced disorder in TBUT was found in seven 21.9% glaucoma patients and was not found in the control group. Basal tear secretion measured by Schirmer 1 testing was found reduced in 87% of glaucoma patients and in 16.7% control group patients. Glaucoma patients on topical intraocular pressure lowering monotherapy showed a significantly higher prevalence of ocular surface disease symptoms, significantly reduced basal tear secretion and destabilisation of tear film in comparison with healthy volunteers.

Abstract (croatian)

Cilj studije je bilo određivanje pojavnosti simptoma suhog oka i stanja suznog filma u glaukomskih bolesnika koji su
liječeni antiglaukomskim lijekovima u obliku kapljica. Glaukomski pacijenti su primali samo jednu vrstu kapi. U istraživanju je sudjelovalo 62 ispitanika koji su bili podijeljeni u dvije skupine: 32 glaukomska ispitanika i 30 zdravih ispitanika
kontrolne skupine. Vrijeme pucanja suznog filma (TBUT Tear film break-up time), Schirmer 1 test i standardizirani
upitnik o simptomima suhog oka provedeni su u obje skupine ispitanika. 50% glaukomskih ispitanika i 25%
ispitanika kontrolne skupine imali su simptome suhog oka. Uznapredovala disfunkcija suznog filma (skraćeno vrijeme
pucanja suznog filma – TBUT) ustanovljena je samo u skupini glaukomskih ispitanika (21,9%). Reduciranu bazalnu
sekreciju mjerenu Schirmer 1 testom imalo je 87% ispitanika glaukomske skupine i 16,7% ispitanika kontrolne skupine.
Glaukomski pacijenti liječeni monoterapijom u obliku kapi imali su značajno više simptoma povezanih sa suhoćom
površine oka, sniženu bazalnu sekreciju suza kao i disfunkciju suznog filma u odnosu na kontrolnu skupinu zdravih
ispitanika.

• Keywords (english): Adult; Aged; Female; Glaucoma/drug therapy; Glaucoma/physiopathology; Humans; Male; Middle Aged; Prospective Studies; Tears/secretion
• Language: english
• Publication type: Professional paper - Review paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 37, no. S1, pp. 137-140
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:152852
• Publication: 2013-04
• Document URL: https://hrcak.srce.hr/102870
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-27 19:54:26