prikaz prve stranice dokumenta Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder
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Scientific paper - Original scientific paper
Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder
Croatian Medical Journal, 55 (2014), 1; 27-37. https://doi.org/10.3325/cmj.2014.55.27
Kalinić, Dubravka; Borovac Štefanović, Leda; Jerončić, Ana; Mimica, Ninoslav; Dodig, Goran; Delaš, Ivančica

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Kalinić, D., Borovac Štefanović, L., Jerončić, A., Mimica, N., Dodig, G. & Delaš, I. (2014). Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder. Croatian Medical Journal, 55. (1), 27-37. doi: 10.3325/cmj.2014.55.27

Kalinić, Dubravka, et al. "Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder." Croatian Medical Journal, vol. 55, no. 1, 2014, pp. 27-37. https://doi.org/10.3325/cmj.2014.55.27

Kalinić, Dubravka, Leda Borovac Štefanović, Ana Jerončić, Ninoslav Mimica, Goran Dodig and Ivančica Delaš. "Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder." Croatian Medical Journal 55, no. 1 (2014): 27-37. https://doi.org/10.3325/cmj.2014.55.27

Kalinić, D., et al. (2014) 'Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder', Croatian Medical Journal, 55(1), pp. 27-37. doi: 10.3325/cmj.2014.55.27

Kalinić D, Borovac Štefanović L, Jerončić A, Mimica N, Dodig G, Delaš I. Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder. Croatian Medical Journal [Internet]. 2014 February [cited 2024 November 23];55(1):27-37. doi: 10.3325/cmj.2014.55.27

D. Kalinić, L. Borovac Štefanović, A. Jerončić, N. Mimica, G. Dodig and I. Delaš, "Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder", Croatian Medical Journal, vol. 55, no. 1, pp. 27-37, February 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:509774. [Accessed: 23 November 2024]

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Metadata
Title (english)Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder
AuthorDubravka Kalinić
AuthorLeda Borovac Štefanović
AuthorAna Jerončić
AuthorNinoslav Mimica
AuthorGoran Dodig
AuthorIvančica Delaš
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
AIM: To explore the association between plasma fatty acids composition and the severity of clinical symptoms in Croatian war veterans with posttraumatic stress disorder (PTSD). ----- METHODS: This cross-sectional study included 62 men diagnosed with PTSD caused by combat activities during the War in Croatia 1991-1995. Clinician-Administered PTSD Scale (CAPS), Hamilton Anxiety Rating Scale (HAM-A), and Hamilton Depression Rating Scale (HAM-D-17) were used. Plasma fatty acids composition was determined by gas chromatography. Data about life-style habits were collected by a structured interview. To evaluate the association between plasma fatty acid levels and PTSD severity scales, multivariate general linear models (GLM) were applied while controlling for different confounders. ----- RESULTS: Significant negative correlations were found between plasma eicosapentaenoic acid (EPA, 20:5n-3) level and the scores on psychological scales (τ = -0.326, P<0.001 for CAPS; τ-0.304, P =0 .001 for HAM-A; and τ = -0.345, P<0.001 for HAM-D-17). GLM confirmed that PTSD severity was affected by EPA (Wilks'Λ = 0.763-0.805, P = 0.006-0.018, ηp 0.195-0.237), arachidonic acid (AA)/EPA (Wilks'Λ = 0.699-0.757, P = 0.004, ηp 0.243-0.301), and dairy products consumption (Wilks'Λ = 0.760-0.791, P = 0.045-0.088, ηp 0.128-0.111). No other fatty acid or dietary/lifestyle variable was significant ( P = 0.362-0.633). ----- CONCLUSION: The study suggests that lower EPA levels are associated with the severity of clinical symptoms in PTSD.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCroatian Medical Journal
Numberingvol. 55, no. 1, pp. 27-37
p-ISSN0353-9504
DOIhttps://doi.org/10.3325/cmj.2014.55.27
URN:NBNurn:nbn:hr:105:509774
Publication2014-02
Document URLhttp://www.cmj.hr/2014/55/1/24577824.htm
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-27 20:09:11