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Scientific paper - Case study
Platelet satellitism in infectious disease?
Biochemia Medica, 25 (2015), 2; 285-294. https://doi.org/10.11613/BM.2015.030
Vidranski, Valentina; Laškaj, Renata; Sikirić, Dubravka; Škerk, Višnja

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Vidranski, V., Laškaj, R., Sikirić, D. & Škerk, V. (2015). Platelet satellitism in infectious disease?. Biochemia Medica, 25. (2), 285-294. doi: 10.11613/BM.2015.030

Vidranski, Valentina, et al. "Platelet satellitism in infectious disease?." Biochemia Medica, vol. 25, no. 2, 2015, pp. 285-294. https://doi.org/10.11613/BM.2015.030

Vidranski, Valentina, Renata Laškaj, Dubravka Sikirić and Višnja Škerk. "Platelet satellitism in infectious disease?." Biochemia Medica 25, no. 2 (2015): 285-294. https://doi.org/10.11613/BM.2015.030

Vidranski, V., et al. (2015) 'Platelet satellitism in infectious disease?', Biochemia Medica, 25(2), pp. 285-294. doi: 10.11613/BM.2015.030

Vidranski V, Laškaj R, Sikirić D, Škerk V. Platelet satellitism in infectious disease?. Biochemia Medica [Internet]. 2015 June 05 [cited 2024 October 07];25(2):285-294. doi: 10.11613/BM.2015.030

V. Vidranski, R. Laškaj, D. Sikirić and V. Škerk, "Platelet satellitism in infectious disease?", Biochemia Medica, vol. 25, no. 2, pp. 285-294, June 2015. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:826740. [Accessed: 07 October 2024]

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Metadata
Title (english)Platelet satellitism in infectious disease?
AuthorValentina Vidranski
AuthorRenata Laškaj
AuthorDubravka Sikirić
AuthorVišnja Škerk
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND: Platelet satellitism is a phenomenon of unknown etiology of aggregating platelets around polymorphonuclear neutrophils and other blood cells which causes pseudothrombocytopenia, visible by microscopic examination of blood smears. It has been observed so far in about a hundred cases in the world. ----- CASE SUBJECT AND METHODS: Our case involves a 73-year-old female patient with a urinary infection. Biochemical serum analysis (CRP, glucose, AST, ALT, ALP, GGT, bilirubin, sodium, potassium, chloride, urea, creatinine) and blood cell count were performed with standard methods on autoanalyzers. Serum protein fractions were examined by electrophoresis and urinalysis with standard methods on autoanalyzer together with microscopic examination of urine sediment. Erythrocyte sedimentation rate, blood culture and urine culture tests were performed with standard methods. ----- RESULTS: Due to typical pathological values for bacterial urinary infection, the patient was admitted to the hospital. Blood smear examination revealed phenomenon, which has persisted for three weeks after the disease has been cured. Blood smears with EDTA as an anticoagulant had platelet satellitism whereas the phenomenon was not observed in tubes with different anticoagulants (Na, Li-heparin) and capillary blood. ----- DISCUSSION: We hypothesize that satellitism was induced by some immunological mechanism through formation of antibodies which have mediated platelets binding to neutrophil membranes and vice versa. Unfortunately we were unable to determine the putative trigger for this phenomenon. To our knowledge this is the second case of platelet satellitism ever described in Croatia.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleBiochemia Medica
Numberingvol. 25, no. 2, pp. 285-294
p-ISSN1330-0962
DOIhttps://doi.org/10.11613/BM.2015.030
URN:NBNurn:nbn:hr:105:826740
Publication2015-06-05
Document URLhttps://doi.org/10.11613/BM.2015.030
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:05:00