Osteoporosis, spinal mobility and chest expansion index in patients with ankylosing spondylitis

Scientific paper - Original scientific paper

• Title (croatian): Osteoporoza, pokretljivost kralješnice i indeks disanja u bolesnika sa ankilozantnim spondilitisom
• Author: Frane Grubišić
• Author: Simeon Grazio
• Author: Antonija Balenović
• Author: Tomislav Nemčić
• Author: Zvonko Kusić
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

To determine the correlation between the bone mineral density (BMD) and spinal mobility and chest expansion index in patients with ankylosing spondylitis. Eighty patients with confirmed diagnosis of ankylosing spondylitis were included in this study. In all of them physical examination was performed including assessment of spinal mobility and chest expansion index. Bone mineral density of the lumbar spine (L1-L4, anteroposterior view) and at the left hip was measured by dual X-ray absorptiometry (DXA) in standard manner According to the WHO classification of osteoporosis, patients were classified in three groups (normal, osteopenic or osteoporotic) depending on the osteoporotic status in lumbar spine, hip and femoral neck region. Eighty patients (46 men and 34 women; age 25-73 years) were included. Mean BMD for lumbar spine was 1.104 +/- 1.043 (T score: 0.67 +/- 2.15) and for total hip was 1.057 +/- 0.899 (T score: -0.28 +/- 2.34). Significant difference in the mobility of thoracic spine was observed in patients in regard to the WHO classification of osteoporosis in lumbar and femoral region (p = 0.031, Oneway Anova for osteoporosis of lumbar region; p = 0.022, Oneway Anova for osteoporosis of total hip region). Mean value for the chest expansion index was 3.07 +/- 1.66 cm. Chest expansion index was significantly reduced in patients having osteoporosis in lumbar and total hip region (p = 0.015, Oneway Anova for osteoporosis of lumbar region; p = 0.038, Oneway Anova for osteoporosis of total hip region). The observation that reduced mobility of thoracic and lumbar spine and chest expansion index occured in patients with low BMD in lumbar and total hip region suggest that osteoporosis should be monitored more frequently in patients with AS.

Abstract (croatian)

U radu se želi odrediti postoji korelacija između mineralne gustoće kostiju i pokretljvosti kralješnice i indeksa disanja
u bolesnika sa ankilozantnim spondilitisom. Istraživanjem je uključeno osamdeset bolesnika sa potvrđenom dijagnozom
ankilozantnog spondilitisa. Klinički pregled bolesnika obuhvatio je mjerenje pokretljivosti kralješnice i indeksa
disanja. Mineralna gustoća kosti (MGK) lumbalne kralješnice (L1–L4, anteroposterior pogled) i lijevog kuka mjerene su
dvostrukom apsorpciometrijom X zraka standardnim načinom. Temeljem WHO klasifikacije osteoporoze, bolesnici su
podijeljeni u tri skupine (normalan, ostepenija ili osteoporoza) ovisno o osteoporotskom statusu u području lumbalne
kralješnice, kuka i području vrata femura. Osamdeset bolesnika (46 muškaraca i 24 žene; raspon godina 25–73) uključeni su u istraživanje. Srednja vrijednosti MGK lumbalne kralješnice iznosila je 1,104±1,043 (T vrijednost: 0,67±2,15) i
za područje kuka 1,057±0,899 (T vrijednost: –0,28±2,34). Značajna razlika u pokretljivosti torakalne kralješnice uočena
je u bolesnika sa osteoporozom lumbalne kralješnice i područja femura obzirom na WHO klasifikaciju (p=0,031,
Oneway Anova za osteoporozu u lumbalnoj kralješnici; p=0,022, Oneway Anova za osteoporozu u području kuka).
Srednja vrijednost indeksa disanja iznosila je 3,07±1,66 cm. Indeks disanja značajno je smanjen u bolesnika koji imaju
osteoporozu u lumbalnoj kralješnici i u području kuka (p=0,015, Oneway Anova za osteoporozu u lumbalnoj kralješnici;
p=0,038, Oneway Anova za osteoporozu u području kuka). Budući da je u bolesnika sa smanjenom MGK u slabinskoj
kralješnici i u području kuka uočena ograničena pokretljivost torakalne i lumbalne kralješnice i indeksa disanja, u
bolesnika sa ankilozantnim spondilitisom osteoporozu bi se trebalo češće detektirati.

• Keywords (english): Adult; Aged; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Osteoporosis/epidemiology; Osteoporosis/physiopathology; Prevalence; Range of Motion, Articular; Spine/physiology; Spondylitis, Ankylosing/epidemiology; Spondylitis, Ankylosing/physiopathology; Thorax/physiology
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 38, no. 1, pp. 63-68
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:064639
• Publication: 2014-03
• Document URL: https://hrcak.srce.hr/120784
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 08:17:57