Corticosteroid therapy in patients with non-arteritic anterior ischemic optic neuropathy

Scientific paper - Original scientific paper

• Title (croatian): Kortikosteroidi u liječenju bolesnika s nearteritičkom prednjom ishemičkom optičkom neuropatijom
• Author: Tomislav Vidović
• Author: Branimir Cerovski
• Author: Sanja Perić
• Author: Rajko Kordić
• Author: Danijela Mrazovac
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Non-arteritic anterior ischemic optic neuropathy is one of the most common conditions affecting the optic nerve in the elderly. It may lead to severe visual loss. Typical symptoms are painless impairment of visual function accompanied by relative afferent pupillary defect, edema of the optic disc and visual field defects. Aim is to present 38 patients with nonarteritic anterior ischemic optic neuropathy who were treated with corticosteroid therapy. This prospective study involved 38 patients, 20 men and 18 women aged 60-75 years who were treated with corticosteroid therapy. The study included patients with visual acuity in the affected eye from 0.1 to 0.8 according to Snellen. Every patient underwent clinical examination, the Octopus 900 perimetry in G program, laboratory testing, while the compressive optic neuropathy was rule out with MSCT of the brain and orbits. The most common forms of visual field defect are altitudinal defect and diffuse depression. Corticosteroid therapy led to recovery in 65% of patient, in 30% of patients did not change, while the deterioration occurred in 5% of patients.

Abstract (croatian)

Autori prikazuju 38 bolesnika s nearteritičkom prednjom ishemičkom optičkom neuropatijom koji su liječeni kortikosteroidima.
U ovom prospektivnom istraživanju sudjelovalo je 38 ispitanika, 20 muškaraca i 18 žena u dobi 60 do 75
godina, koji su liječeni kortikosteroidima. U istraživanje su uključeni bolesnici s vidnom oštrinom na zahvaćenom oku
od 0,1 do 0,8 prema Snellenu. Svi su klinički pregledani uz Octopus 900 perimetriju u G programu i laboratorijsku
opservaciju, dok se kompresivna optička neuropatija isključila MSCTom mozga i orbita. Najčešći oblici oštećenja vidnog
polja bili su altitudinalni defekt i difuzna depresija mrežnične osjetljivosti. Kortikosteroidna terapija dovela je do oporavka
u 65% bolesnika, u 30% bolesnika nije bilo promjena, dok je pogoršanje nastupilo u 5% bolesnika.

• Keywords (english): Adrenal Cortex Hormones/therapeutic use; Aged; Female; Humans; Male; Methylprednisolone/therapeutic use; Middle Aged; Optic Disk; Optic Nerve/physiopathology; Optic Neuropathy, Ischemic/drug therapy; Prospective Studies; Visual Acuity; Visual Field Tests
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 39, no. 1, pp. 63-66
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:241611
• Publication: 2015-03
• Document URL: https://hrcak.srce.hr/147689
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 08:25:07