Antithrombotics in heart failure

Scientific paper - Review paper

• Author: Davor Miličić
• Author: Jure Samardžić
• Author: Mate Petričević
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Heart failure is a common clinical condition associated with high morbidity and mortality rate despite significant improvements in pharmacotherapy and implementation of medical procedures. Patients with heart failure are at an increased risk of developing arterial and venous thrombosis, which contribute to the high rate of adverse events and fatal outcomes. Many heart failure patients routinely receive antithrombotic therapy due to the presence of a specific indication for its use, like ischemic heart disease or atrial fibrillation. However, there is no solid evidence to support the routine use of antithrombotic agents in all heart failure patients. This article reviews the evidence for using antithrombotic therapy in heart failure patients.

Abstract (croatian)

Antitrombotici u liječenju zatajenja srca ----- Zatajenje srca često je kliničko stanje povezano s visokim pobolom i smrtnošću unatoč brzom razvoju farmakoterapijskih i medicinskih postupaka. Pacijenti sa zatajenjem srca imaju povećan rizik obolijevanja od arterijske i venske tromboze, što doprinosi visokoj stopi neželjenih događaja i smrtnih ishoda. Mnogi bolesnici rutinski se liječe antitromboticima kada postoji specifična indikacija za njihovu uporabu, kao što je ishemijska bolest srca ili fibrilacija atrija. Međutim, ne postoje dokazi koji podupiru rutinsku uporabu antitrombotika kod svih pacijenata sa zatajenjem srca. Ovaj članak vrši pregled dokaza u prilog korištenja antitrombotika kod pacijenata sa zatajenjem srca.

• Keywords (english): Fibrinolytic Agents/therapeutic use; Heart Failure/drug therapy; Humans; Thromboembolism/prevention & control
• Language: english
• Publication type: Scientific paper - Review paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Croatian Medical Journal
• Numbering: vol. 55, no. 6, pp. 621-627
• p-ISSN: 0353-9504
• DOI: https://doi.org/10.3325/cmj.2014.55.621
• URN:NBN: urn:nbn:hr:105:975430
• Publication: 2014-12
• Document URL: https://doi.org/10.3325/cmj.2014.55.621
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 08:26:33