Dermoscopy and early melanoma

Professional paper - Review paper

• Title (croatian): Dermatoskopija i rani melanom
• Author: Danijela Ćurković
• Author: Zrinjka Paštar
• Author: Krešimir Kostović
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

The lack of effective therapies for patients with advanced melanoma establishes an early recognition as the aim of clinical and dermoscopic examination, which is the most important factor for improving patient survival and decreases the treatment and management costs. Melanoma in situ is the earliest stage of melanoma. The features of early melanomas, especially in those lesions smaller than 3mm, can be very subtle clinically, dermoscopically and pathohistologically, and it is often impossible to discriminate between a melanoma and nevus. Clinically, de novo melanomas are small brown to black macula with an irregular outline. In melanomas developing in a nevus, there is an asymmetry of the lesion with marked change in color and/or shape of the pre-existing nevus. Dermoscopically, early stages of melanoma show the same global features as thicker melanomas, but in a more subtle way. Asymmetry is the most important parameter; multiple colors are rare. Significant local melanoma-specific criteria, especially when present at the periphery, are irregular pigment network, irregular streaks, and irregular dots/globules, while blue-white structures are rarely found.

Abstract (croatian)

DERMATOSKOPIJA I RANI MELANOM ----- Obzirom na nedostatak učinkovite terapije za uznapredovali melanom, rano prepoznavanje melanoma je osnovni
cilj kliničkog i dermoskopskog pregleda, jer je to najvažniji čimbenik za unapređenje preživljavanja pacijenata s melanomom.
Melanom in situ je najranija faza melanoma. Značajke ranog melanoma, posebno u promjenama manjima od 3
mm, mogu biti vrlo suptilne klinički, dermoskopski i patohistološki, a često je nemoguće izdiferencirati melanom od
nevusa. Klinički, de novo melanomi su male smeđe do crne makule s nepravilnim rubovima. U melanomima koji se
razvijaju iz nevusa postoji asimetrija promjene sa značajnom promjenom u boji i/ili obliku već postojećeg nevusa. Dermoskopski,
rane faze melanoma pokazuju iste, ali diskretnije globalne/osnovne karkateristike kao deblji/uznapredovali
melanomi. Asimetrija je najvažniji parametar; više boja je rijetkost. Značajni lokalno-specifični kriteriji melanoma,
posebno kada su prisutni na periferiji, su nepravilna pigmentna mreža, nepravilni pigmentni izdanci i nepravilne
točkaste strukture, a plavo-bijele strukture se rijetko nalaze.

• Keywords (english): Dermoscopy / methods; Early Detection of Cancer / methods; Humans; Melanoma / complications; Melanoma / diagnosis; Melanoma / pathology; Nevus, Pigmented / complications; Nevus, Pigmented / pathology; Skin Neoplasms / complications; Skin Neoplasms / diagnosis; Skin Neoplasms / pathology
• Language: english
• Publication type: Professional paper - Review paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 39, no. 3, pp. 791-795
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:024272
• Publication: 2015-09
• Document URL: https://hrcak.srce.hr/166384
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 08:29:34