prikaz prve stranice dokumenta A new look at cerebrospinal fluid movement
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Scientific paper - Original scientific paper
A new look at cerebrospinal fluid movement
Fluids and Barriers of the CNS, 11 (2014); 16. https://doi.org/10.1186/2045-8118-11-16
Orešković, Darko; Klarica, Marijan

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Orešković, D. & Klarica, M. (2014). A new look at cerebrospinal fluid movement. Fluids and Barriers of the CNS, 11., 16. doi: 10.1186/2045-8118-11-16

Orešković, Darko and Marijan Klarica. "A new look at cerebrospinal fluid movement." Fluids and Barriers of the CNS, vol. 11, 2014, p. 16. https://doi.org/10.1186/2045-8118-11-16

Orešković, Darko and Marijan Klarica. "A new look at cerebrospinal fluid movement." Fluids and Barriers of the CNS 11 (2014): 16. https://doi.org/10.1186/2045-8118-11-16

Orešković, D. and Klarica, M. (2014) 'A new look at cerebrospinal fluid movement', Fluids and Barriers of the CNS, 11, p. 16. doi: 10.1186/2045-8118-11-16

Orešković D, Klarica M. A new look at cerebrospinal fluid movement. Fluids and Barriers of the CNS [Internet]. 2014 July 27 [cited 2025 January 02];11:16. doi: 10.1186/2045-8118-11-16

D. Orešković and M. Klarica, "A new look at cerebrospinal fluid movement", Fluids and Barriers of the CNS, vol. 11, p. 16, July 2014. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:568101. [Accessed: 02 January 2025]

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Metadata
Title (english)A new look at cerebrospinal fluid movement
AuthorDarko Orešković
AuthorMarijan Klarica
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Basic Medical Sciences
Abstract (english)
Brinker et al. extensively reviewed recent findings about CSF circulation in a recent article: "A new look at cerebrospinal circulation", but did not analyze some important available data in sufficient detail. For example, our findings as well as some clinical data and experimental results obtained from different animal species, do not support unidirectional CSF circulation but strongly suggest that there are cardiac cycle-dependent systolic-diastolic to-and-fro cranio-spinal CSF movements. These are based on: a) physiological oscillations of arterial and venous blood during cranio-spinal blood circulation; b) respiratory activity, and c) body activity and posture. That kind of complex CSF movement could explain the observed distribution of many different substances in all directions along the CSF system and within central nervous system tissue. It seems that efflux transport systems at capillary endothelium may be more important for brain homeostasis than the removal of metabolites by CSF flow. Thus, when discussing the CSF dynamics we suggest that a more appropriate term would be CSF movement rather than CSF circulation.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleFluids and Barriers of the CNS
Numberingvol. 11, p. 16
p-ISSN2045-8118
DOIhttps://doi.org/10.1186/2045-8118-11-16
URN:NBNurn:nbn:hr:105:568101
Publication2014-07-27
Document URLhttps://doi.org/10.1186/2045-8118-11-16
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 08:36:13