Klinički pristup ginekomastiji

Scientific paper - Original scientific paper

• Title (english): Clinical evaluation of gynecomastia
• Author: Anela Novak
• Author: Darko Kaštelan
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Gynecomastia is characterized by the ennlargement of the male breast caused by glandular proliferation. Gynecomastia occurs when the estrogen-to-androgen ratio is disrupted, in plasma or locally in the breast tissue. The etiology is usually benign. Physiologic gynecomastia is common in newborns, adolescents, and older men. Nonphysiologic gynecomastia may be caused by chronic conditions (e.g. hypogonadism, liver cirrhosis, renal insufficiency), use of certain medications or substances, and, rarely tumors. The diagnostic evaluation starts with careful history taking and physical examination which may be followed by extensive work-up that includes selective imaging and laboratory testing. Discontinuing the use of contributing medications and treating the underlying disease are the mainstay of treatment.

Abstract (croatian)

Ginekomastijom nazivamo povećanje dojke u muškaraca uzrokovano proliferacijom žljezdanog tkiva. Posljedica je poremećenog omjera estrogena i androgena u plazmi ili lokalno u žljezdanom tkivu dojke. Uzroci ginekomastije uglavnom su benigni. Fiziološka ginekomastija česta je pojava i nalazimo ju u novorođenčadi, u pubertetu i u starijoj dobi. Nefiziološka ginekomastija može nastati kao posljedica raznih kroničnih bolesti (npr. hipogonadizam, ciroza jetre, zatajenje bubrega), upotrebe lijekova ili drugih tvari i, rijetko, tumora. Obradu započinjemo pažljivim uzimanjem anamneze i fizikalnim pregledom, nakon čega, prema potrebi, obradu proširujemo ciljanim radiološkim i laboratorijskim pretragama. Terapija ginekomastije temelji se na liječenju bolesti koja ju je uzrokovala, odnosno prekidu primjene lijekova/tvari koji su je potencijalno izazvali.

• Language: croatian
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Liječnički vjesnik
• Numbering: vol. 139, no. 3-4, pp. 75-81
• p-ISSN: 0024-3477
• URN:NBN: urn:nbn:hr:105:008685
• Publication: 2017-03
• Document URL: https://hrcak.srce.hr/184338
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 09:40:10