prikaz prve stranice dokumenta Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes
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Scientific paper - Original scientific paper
Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes
Journal of Stroke, 20 (2018), 3; 373-384. https://doi.org/doi:10.5853/jos.2018.01305
Pikija, Slaven; Trkulja, Vladimir; Ramesmayer, Christian; Mutzenbach, Johannes S.; Killer-Oberpfalzer, Monika; Hecker, Constantin; Bubel, Nele; Füssel, Michael Ulrich; Sellner, Johann

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Pikija, S., Trkulja, V., Ramesmayer, C., Mutzenbach, J. S., Killer Oberpfalzer, M., Hecker, C. ... Sellner, J. (2018). Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes. Journal of Stroke, 20. (3), 373-384. doi: doi:10.5853/jos.2018.01305

Pikija, Slaven, et al. "Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes." Journal of Stroke, vol. 20, no. 3, 2018, pp. 373-384. https://doi.org/doi:10.5853/jos.2018.01305

Pikija, Slaven, Vladimir Trkulja, Christian Ramesmayer, Johannes S. Mutzenbach, Monika Killer Oberpfalzer, Constantin Hecker, Nele Bubel, Michael Ulrich Füssel and Johann Sellner. "Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes." Journal of Stroke 20, no. 3 (2018): 373-384. https://doi.org/doi:10.5853/jos.2018.01305

Pikija, S., et al. (2018) 'Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes', Journal of Stroke, 20(3), pp. 373-384. doi: doi:10.5853/jos.2018.01305

Pikija S, Trkulja V, Ramesmayer C, Mutzenbach JS, Killer Oberpfalzer M, Hecker C, and sur.. Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes. Journal of Stroke [Internet]. 2018 September 20 [cited 2024 October 31];20(3):373-384. doi: doi:10.5853/jos.2018.01305

S. Pikija, et al., "Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes", Journal of Stroke, vol. 20, no. 3, pp. 373-384, September 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:609494. [Accessed: 31 October 2024]

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Metadata
Title (english)Higher blood pressure duringeEndovascular thrombectomy in anterior circulation stroke is associated with better outcomes
AuthorSlaven Pikija
AuthorVladimir Trkulja
AuthorChristian Ramesmayer
AuthorJohannes S. Mutzenbach
AuthorMonika Killer-Oberpfalzer
AuthorConstantin Hecker
AuthorNele Bubel
AuthorMichael Ulrich Füssel
AuthorJohann Sellner
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
BACKGROUND AND PURPOSE: Reports investigating the relationship between in-procedure blood pressure (BP) and outcomes in patients undergoing endovascular thrombectomy (EVT) due to anterior circulation stroke are sparse and contradictory. ----- METHODS: Consecutive EVT-treated adults (modern stent retrievers, BP managed in line with the recommendations, general anesthesia, invasive BP measurements) were evaluated for associations of the rate of in-procedure systolic BP (SBP) and mean arterial pressure (MAP) excursions to >120%/<80% of the reference values (serial measurements at anesthesia induction) and of the reference BP/weighted in-procedure mean BP with post-procedure imaging outcomes (ischemic lesion volume [ILV], hemorrhages) and 3-month functional outcome (modified Rankin Scale [mRS], score 0 to 2 vs. 3 to 6). ----- RESULTS: Overall 164 patients (70.7% pharmacological reperfusion, 80.5% with good collaterals, 73.8% with successful reperfusion) were evaluated for ILV (range, 0 to 581 cm3) and hemorrhages (incidence 17.7%). Higher rate of in-procedure SBP/MAP excursions to >120% was independently associated with lower ILV, while higher in-procedure mean SBP/MAP was associated with lower odds of hemorrhages. mRS 0-2 was achieved in 75/155 (48.4%) evaluated patients (nine had missing mRS data). Higher rate of SBP/MAP excursions to >120% and higher reference SBP/MAP were independently associated with higher odds of mRS 0-2, while higher ILV was associated with lower odds of mRS 0-2. Rate of SBP/MAP excursions to <80% was not associated with any outcome. ----- CONCLUSION: s In the EVT-treated patients with BP managed within the recommended limits, a better functional outcome might be achieved by targeting in-procedure BP that exceeds the preprocedure values by more than 20%.
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleJournal of Stroke
Numberingvol. 20, no. 3, pp. 373-384
p-ISSN2287-6391
DOIhttps://doi.org/doi:10.5853/jos.2018.01305
URN:NBNurn:nbn:hr:105:609494
Publication2018-09-20
Document URLhttp://doi.org/10.5853/jos.2018.01305
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:03:18