prikaz prve stranice dokumenta Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension
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Scientific paper - Original scientific paper
Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension
Blood Pressure, 27 (2018), 4; 240-246. https://doi.org/doi:10.1080/08037051.2018.1476055
Prijić, Radovan; Premužić, Vedran; Brinar, Marko; Krznarić, Željko; Jelaković, Bojan; Čuković-Čavka, Silvija

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Prijić, R., Premužić, V., Brinar, M., Krznarić, Ž., Jelaković, B. & Čuković Čavka, S. (2018). Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension. Blood Pressure, 27. (4), 240-246. doi: doi:10.1080/08037051.2018.1476055

Prijić, Radovan, et al. "Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension." Blood Pressure, vol. 27, no. 4, 2018, pp. 240-246. https://doi.org/doi:10.1080/08037051.2018.1476055

Prijić, Radovan, Vedran Premužić, Marko Brinar, Željko Krznarić, Bojan Jelaković and Silvija Čuković Čavka. "Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension." Blood Pressure 27, no. 4 (2018): 240-246. https://doi.org/doi:10.1080/08037051.2018.1476055

Prijić, R., et al. (2018) 'Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension', Blood Pressure, 27(4), pp. 240-246. doi: doi:10.1080/08037051.2018.1476055

Prijić R, Premužić V, Brinar M, Krznarić Ž, Jelaković B, Čuković Čavka S. Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension. Blood Pressure [Internet]. 2018 August [cited 2024 November 07];27(4):240-246. doi: doi:10.1080/08037051.2018.1476055

R. Prijić, V. Premužić, M. Brinar, Ž. Krznarić, B. Jelaković and S. Čuković Čavka, "Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension", Blood Pressure, vol. 27, no. 4, pp. 240-246, August 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:308581. [Accessed: 07 November 2024]

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Metadata
Title (english)Increased arterial stiffness – similar findings in patients with inflammatory bowel disease without prior hypertension or diabetes and in patients with well-controlled hypertension
AuthorRadovan Prijić
AuthorVedran Premužić
AuthorMarko Brinar
AuthorŽeljko Krznarić
AuthorBojan Jelaković
AuthorSilvija Čuković-Čavka
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
PURPOSE: Chronic inflammatory diseases are related with earlier onset of atherosclerosis. We hypothesized that inflammatory bowel disease patients with chronic, systemic inflammation have an increased arterial stiffness associated with the disease duration. Also, we wanted to compare arterial stiffness markers between inflammatory bowel disease and well-controlled hypertension patients. ----- MATERIALS AND METHODS: A total of 89 inflammatory bowel disease patients (60 patients with Crohn's disease and 29 patients with ulcerative colitis, age range 20-64 years) without history of arterial hypertension or diabetes were enrolled and age matched with a control group of patients (73 patients, age range 25-69 years, 41 (56.1%) males) with known history of well-controlled arterial hypertension. We have used a noninvasive device that simultaneously measures brachial blood pressure and estimates PWV and AIx in inflammatory bowel disease and hypertension groups of patients. ----- RESULTS: Patients with pathological PWV values were significantly older, had significantly longer duration of inflammatory bowel disease, higher values of serum cholesterol and HDL-cholesterol, and higher AIx (17.4% vs. 9.8%) (all p < .05). Higher PWV was associated with age and duration of inflammatory bowel disease in the linear regression model. PWV values were higher in hypertensive patients in the first two age quartiles while interestingly, in the last two quartiles, PWV was lower than in inflammatory bowel disease group of patients. ----- CONCLUSIONS: Chronic subclinical inflammation is responsible for dyslipidemia and accelerated atherosclerosis which consequently alterates arterial elasticity. Inflammatory bowel disease and its duration should also be considered a risk factor for subclinical organ damage, as well as hypertension.
Keywords (english)
Languageenglish
Publication typeScientific paper - Original scientific paper
Publication statusPublished
Peer reviewPeer review
Publication versionAccepted version
Journal titleBlood Pressure
Numberingvol. 27, no. 4, pp. 240-246
p-ISSN0803-7051
DOIhttps://doi.org/doi:10.1080/08037051.2018.1476055
URN:NBNurn:nbn:hr:105:308581
Publication2018-08
Document URLhttp://doi.org/10.1080/08037051.2018.1476055
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:16:17