prikaz prve stranice dokumenta Epigenetics and testicular germ cell tumors
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Scientific paper - Review paper
Epigenetics and testicular germ cell tumors
Gene, 661 (2018); 22-33. https://doi.org/10.1016/j.gene.2018.03.072
Buljubašić, Robert; Buljubašić, Maja; Bojanac, Ana Katušić; Ulamec, Monika; Vlahović, Maja; Ježek, Davor; Bulić-Jakuš, Floriana; Sinčić, Nino

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Buljubašić, R., Buljubašić, M., Bojanac, A. K., Ulamec, M., Vlahović, M., Ježek, D. ... Sinčić, N. (2018). Epigenetics and testicular germ cell tumors. Gene, 661., 22-33. doi: 10.1016/j.gene.2018.03.072

Buljubašić, Robert, et al. "Epigenetics and testicular germ cell tumors." Gene, vol. 661, 2018, pp. 22-33. https://doi.org/10.1016/j.gene.2018.03.072

Buljubašić, Robert, Maja Buljubašić, Ana Katušić Bojanac, Monika Ulamec, Maja Vlahović, Davor Ježek, Floriana Bulić Jakuš and Nino Sinčić. "Epigenetics and testicular germ cell tumors." Gene 661 (2018): 22-33. https://doi.org/10.1016/j.gene.2018.03.072

Buljubašić, R., et al. (2018) 'Epigenetics and testicular germ cell tumors', Gene, 661, pp. 22-33. doi: 10.1016/j.gene.2018.03.072

Buljubašić R, Buljubašić M, Bojanac AK, Ulamec M, Vlahović M, Ježek D, and sur.. Epigenetics and testicular germ cell tumors. Gene [Internet]. 2018 June 30 [cited 2024 December 22];661:22-33. doi: 10.1016/j.gene.2018.03.072

R. Buljubašić, et al., "Epigenetics and testicular germ cell tumors", Gene, vol. 661, pp. 22-33, June 2018. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:076569. [Accessed: 22 December 2024]

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Metadata
Title (english)Epigenetics and testicular germ cell tumors
AuthorRobert Buljubašić
AuthorMaja Buljubašić
AuthorAna Katušić Bojanac
AuthorMonika Ulamec
AuthorMaja Vlahović
AuthorDavor Ježek
AuthorFloriana Bulić-Jakuš
AuthorNino Sinčić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewing TGCT-tumorigenesis with an emphasis on epigenetics. Epigenetic mechanisms such as DNA methylation and histone modifications together with RNA interference that all change gene expression are driving early spermatogenesis. Deregulation of normal development might lead to a testicular germ cell neoplasia in situ (GCNIS), from which TGCTs originate. The breakthrough epigenetic research, both in normal development and TGCT tumorigenesis, has been going on to find better biomarkers and therapy for this type of tumors.
Keywords (english)
Languageenglish
Publication typeScientific paper - Review paper
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleGene
Numberingvol. 661, pp. 22-33
p-ISSN0378-1119
DOIhttps://doi.org/10.1016/j.gene.2018.03.072
URN:NBNurn:nbn:hr:105:076569
Publication2018-06-30
Document URLhttps://doi.org/10.1016/j.gene.2018.03.072
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 10:16:58