Intracranial mature teratoma in an adult patient: a case report

Scientific paper - Case study

• Author: Dominik Romić
• Author: Marina Raguž
• Author: Petar Marčinković
• Author: Patricija Sesar
• Author: Martina Špero
• Author: Zrinka Čolak Romić
• Author: Domagoj Dlaka
• Author: Darko Chudy
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

Introduction: Primary intracranial teratoma is a subtype of germ cell tumors, classified into three subtypes. They occur very rarely, with only several reported individual cases in adults. ----- Case Description: We present a patient with an intermittent headache in the right frontal region. Magnetic resonance imaging (MRI) revealed a right sided high frontal parasagittal mass that compressed the falx, the right lateral ventricle, as well as the brain parenchyma. Patient underwent surgical treatment. Histopathological analysis described mature teratoma. Four months after the surgical treatment there were no signs of residual intracranial mass or relapse. ----- Discussion: Primary intracranial teratoma in adults has a nonspecific clinical presentation. MRI reveals a solitary irregular mass with multilocularity and mixed signals derived from different tissues. The patients age, biochemical markers, and patohistological analysis are necessary to confirm the diagnosis. ----- Conclusion: Teratoma treatment strategy still remains controversial. It includes radical resection whenever possible. Since the residual portion of mature teratoma may contain part of immature or malignant tissue, tumor recurrence after surgical removal is possible. Also, new tumor mass could occur at other sites intracranial after the initial one was removed. Thus, although patients usually recover, they should be followed-up for a long period of time.

• Language: english
• Publication type: Scientific paper - Case study
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Journal of Neurological Surgery Reports
• Numbering: vol. 80, no. 01, pp. e14-e17
• p-ISSN: 2193-6358
• DOI: https://doi.org/10.1055/s-0039-1685213
• URN:NBN: urn:nbn:hr:105:942852
• Publication: 2019-01
• Document URL: http://doi.org/10.1055/s-0039-1685213
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 10:35:24