Serum immunoglobulins IgG, IgA and IgM in patients with oral lichen ruber

Scientific paper - Original scientific paper

• Author: Dolores Biočina-Lukenda
• Author: Ana Cekić-Arambašin
• Author: Jasenka Markeljević
• Author: Dino Buković
• Author's institution: University of Zagreb; School of Medicine
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences

Abstract (english)

The aim of this study was to determine level of serum IgA, IgG and IgM in patients with OLR as indicators of humoral immunity which might reflect cell-mediated immunity. This study was conducted on 30 patients (age 60.17 +/- 11.75) with clinically and histopathologically confirmed diagnosis of OLR and 30 healthy controls (age 56.16 +/- 11.82) Determination of serum IgA, IgG and IgM was performed by use of standard laser nephelometry in both patients and controls. Statistical analysis was done using Mann-Whitney U test and the level of significance was determined as p values lower than 0.05. Serum IgA and IgM in patients with OLR were significantly increased in comparison to the control group, while serum IgG levels were higher in patients with OLR but they did not reach significance. We might conclude that elevated levels of serum IgA and IgM show that humoral immunity is implicated in the pathogenesis of OLR.

• Keywords (english): Immunoglobulins - blood; Lichen Planus, Oral - immunology; Female; Humans; Immunoglobulin A - blood; Immunoglobulin G - blood; Immunoglobulin M - blood; Male; Middle Aged
• Language: english
• Publication type: Scientific paper - Original scientific paper
• Publication status: Published
• Peer review: Peer review
• Publication version: Published version
• Journal title: Collegium Antropologicum
• Numbering: vol. 32, no. 1, pp. 161-163
• p-ISSN: 0350-6134
• URN:NBN: urn:nbn:hr:105:800158
• Publication: 2008-03
• Document URL: https://hrcak.srce.hr/22831
• Type of resource: Text
• Access conditions: Open access
• Created on: 2024-03-28 10:45:27