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Scientific paper - Case study
Myeloid sarcoma involving the breast
Collegium Antropologicum, 34 (2010), 2; 641-644. urn:nbn:hr:105:645546
Jelić-Puškarić, Biljana; Ostojić-Kolonić, Slobodanka; Planinc-Peraica, Ana; Obad-Kovačević, Dragica; Kardum-Skelin, Ika; Jakšić, Branimir

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Jelić Puškarić, B., Ostojić Kolonić, S., Planinc Peraica, A., Obad Kovačević, D., Kardum Skelin, I. & Jakšić, B. (2010). Myeloid sarcoma involving the breast . Collegium Antropologicum, 34. (2), 641-644. Retrieved from https://urn.nsk.hr/urn:nbn:hr:105:645546

Jelić Puškarić, Biljana, et al. "Myeloid sarcoma involving the breast ." Collegium Antropologicum, vol. 34, no. 2, 2010, pp. 641-644. https://urn.nsk.hr/urn:nbn:hr:105:645546

Jelić Puškarić, Biljana, Slobodanka Ostojić Kolonić, Ana Planinc Peraica, Dragica Obad Kovačević, Ika Kardum Skelin and Branimir Jakšić. "Myeloid sarcoma involving the breast ." Collegium Antropologicum 34, no. 2 (2010): 641-644. https://urn.nsk.hr/urn:nbn:hr:105:645546

Jelić Puškarić, B., et al. (2010) 'Myeloid sarcoma involving the breast ', Collegium Antropologicum, 34(2), pp. 641-644. Available at: https://urn.nsk.hr/urn:nbn:hr:105:645546 (Accessed 15 March 2025)

Jelić Puškarić B, Ostojić Kolonić S, Planinc Peraica A, Obad Kovačević D, Kardum Skelin I, Jakšić B. Myeloid sarcoma involving the breast . Collegium Antropologicum [Internet]. 2010 June [cited 2025 March 15];34(2):641-644. Available at: https://urn.nsk.hr/urn:nbn:hr:105:645546

B. Jelić Puškarić, S. Ostojić Kolonić, A. Planinc Peraica, D. Obad Kovačević, I. Kardum Skelin and B. Jakšić, "Myeloid sarcoma involving the breast ", Collegium Antropologicum, vol. 34, no. 2, pp. 641-644, June 2010. [Online]. Available at: https://urn.nsk.hr/urn:nbn:hr:105:645546. [Accessed: 15 March 2025]

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Metadata
Title (english)Myeloid sarcoma involving the breast
Title (croatian)Mijeloidni sarkom dojke
AuthorBiljana Jelić-Puškarić
AuthorSlobodanka Ostojić-Kolonić
AuthorAna Planinc-Peraica
AuthorDragica Obad-Kovačević
AuthorIka Kardum-Skelin
AuthorBranimir Jakšić
Author's institutionUniversity of Zagreb
School of Medicine
Scientific / art field,
discipline and subdiscipline		BIOMEDICINE AND HEALTHCARE
Clinical Medical Sciences
Abstract (english)
Myeloid sarcoma is a tumor mass with extramedullary growth pattern, composed of myeloblasts or immature myeloid cells. The development of myeloid sarcoma may precede or concur with acute or chronic myeloid leukemia (AML or CML) or other myeloproliferative diseases or myelodysplastic syndromes (MDS). Isolated myeloid sarcoma of the breast is very rare. A case is presented of a 25-year-old, previously healthy woman that presented to our department for a palpable node, 5 x 2 cm in size, in the upper medial quadrant of her left breast. Fine needle aspiration (FNA) produced a sample consisting of medium sized blasts. Additional work-up revealed anemia, thrombocytopenia and leukocytosis, along with atypical blasts detected in peripheral blood and bone marrow smear. Based on the morphology, cytochemical characteristics and immature cell immunophenotype, it was considered a case of acute myeloid leukemia without maturation. In spite of intensive chemotherapy, the patient died within a year of diagnosis. In cases of isolated breast myeloid sarcoma, the diagnosis can be missed if the possibility of myeloid sarcoma is not remembered on differential diagnosis of a breast neoplasm.
Abstract (croatian)
Mijeloidni sarkom je ekstramedularna tumorska masa građena od mijeloblasta ili nezrelih mijeloičnih stanica. Može predhoditi ili se javiti istovremeno s akutnom ili kroničnom mijeloičnom leukemijom ili drugim tipovina mijeloproliferativnih bolesti ili mijelodisplastičnih sindroma. Izolirani mijeloidni sarkom dojke javlja se vrlo rijetko. Prikazujemo slučaj dvadesetpetogodišnje, do tada zdrave žene koja se javlja na kliniku radi palpabilnog čvora, veličine 5x2 cm u području gornjeg medijalnog kvadranta lijeve dojke. Citološkom punkcijom čvora tankom iglom dobije se uzorak srednje velikih blasta. U laboratorijskim nalazima nađe se anemija, trombocitopenija i leukocitoza, uz prisutne atipične blaste u razmazu periferne krvi i punktatu koštane srži. Obzirom na morfologiju, citokemijska obilježja i imunofenotip nezrelih stanica zaključeno je da se radi o akutnoj mijeločnoj leukemiji bez sazrijevanja. Unatoč intezivnoj kemoterapiji pacijentica umire unutar godinu dana od postavljnja dijagnoze. U slučaju izoliranog mijeloidnog srkoma dojke može se previdjeti točna dijagnoza ako se u diferencijalnoj dijagnozi tumora dojke ne razmišlja o mijeloidnom sarkomu.
Keywords (english)
Languageenglish
Publication typeScientific paper - Case study
Publication statusPublished
Peer reviewPeer review
Publication versionPublished version
Journal titleCollegium Antropologicum
Numberingvol. 34, no. 2, pp. 641-644
p-ISSN0350-6134
URN:NBNurn:nbn:hr:105:645546
Publication2010-06
Document URLhttps://hrcak.srce.hr/56504
Type of resourceText
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2024-03-28 11:47:44