Kvaliteta života osoba oboljelih od sistemskog eritemskog lupusa

master's thesis

• Title (english): Quality of life in patients with systemic lupus erythematosus
• Author: Petra Plivelić
• Mentor: Iskra Alexandra Nola (mentor)
• Committee member: Milan Milošević (predsjednik povjerenstva)
• Committee member: Ksenija Vitale (član povjerenstva)
• Committee member: Iskra Alexandra Nola (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2023-09-19, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Public Health and Health Care

Abstract

Kronične bolesti postale su dio svakodnevnog života modernog čovjeka. Sistemski
eritemski lupus (SLE) kao jedna od brojnih autoimunih kroničnih bolesti može imati
tijek bez značajnijeg utjecaja na svakodnevni život bolesnika, ali može dovesti i do
relapsa uz širenje na organe, uzrokujući invaliditet ili ugrožavanje života. Zdravlje je
jedan od čimbenika koji značajno utječu na kvalitetu života. Individualna samoprocjena
zdravstvenog statusa i kvalitete života sastavni je dio istraživanja povezanih s
procjenom kvalitete života osoba oboljelih od kroničnih bolesti. Cilj ovog rada bio je
ispitati kvalitetu života kod osoba s aktivnom i inaktivnom fazom SLE te ih usporediti
s obzirom na duljinu trajanja bolesti. U istraživanju je sudjelovalo 100 ispitanika
oboljelih od SLE. Kvaliteta života ispitana je korištenjem SF-36 upitnika uz sociodemografske podatke, podatke o duljini trajanja bolesti i fazom bolesti potvrđene od
strane imunoreumatologa na zadnjoj kontroli. Rezultati su pokazali da postoji razlika
u kvaliteti života u odnosu na aktivnu tj. inaktivnu fazu bolesti. Percepcija kvalitete
života ispitanika statistički je značajno bila povezana s fizičkim funkcioniranjem
(p=0,011), tjelesnim bolovima (p=0,001), ograničenjima uslijed fizičkih teškoća
(p=0,004), percepcijom općeg zdravlja (p=0,017) te socijalnim funkcioniranjem
(p=0,009) u odnosu na aktivnost bolesti. Kvaliteta života ispitanika nije bila statistički
značajno povezana s ograničenjima zbog emocionalnih teškoća (p=0,091), psihičkim
zdravljem (p=0,112) te vitalnosti i energijom (p=0,138) u odnosu na aktivnost bolesti.
Nije ustanovljena statistički značajna povezanost niti jedne ispitivane dimenzije
kvalitete života u odnosu na duljinu trajanja bolesti.

Abstract (english)

Chronic diseases have become a part of the everyday life of modern lifestyle. Systemic
lupus erythematosus (SLE), as one of numerous autoimmune chronic diseases, can
have a course without significant impact on the patient's daily life, but it can also lead
to relapses involving organs, causing disability or life-threatening situations. Health is
one of the factors that significantly affect the quality of life. Individual self-assessment
of health status and quality of life is an integral part of research related to the
assessment of the quality of life of individuals with chronic diseases. The aim of this
study was to examine the quality of life in individuals with active and inactive phases
of SLE and to compare them due to the duration of the disease. The study included
100 participants with SLE. Quality of life was assessed using the SF-36 questionnaire
along with socio-demographic data, data on the duration of the disease, and the
disease phase confirmed by an immunorheumatologist during the most recent
examination. The results showed that there is a difference in the quality of life’
perception between the active and inactive phases of the disease among examinees.
The quality of life of the participants was statistically significantly associated with
physical functioning (p=0.011), bodily pain (p=0.001), limitations due to physical
difficulties (p=0.004), perception of general health (p=0.017), and social functioning
(p=0.009) in relation to disease activity. The quality of life of the participants was not
statistically significantly associated with limitations due to emotional difficulties
(p=0.091), mental health (p=0.112), and vitality/energy (p=0.138) in relation to disease
activity. No statistically significant association was found between any of the examined
dimensions of quality of life and the duration of the disease.

• Keywords: autoimuna bolest; kvaliteta života; sestrinstvo; sistemski eritemski lupus; SF-36
• Keywords (english): Autoimmune Disease; Quality of Life; Nursing; Systemic Lupus Erythematosus; SF-36
• Language: croatian
• URN:NBN: urn:nbn:hr:105:436125
• Study programme: Title: Studies in Nursing; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra sestrinstva (magistar/magistra sestrinstva)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-04-18 11:34:31