Dijagnostika i kirurško liječenje tumora pluća

master's thesis

• Title (english): Diagnosis and surgical treatment of lung tumors
• Author: Duje Dražin
• Mentor: Tomislav Bečejac (mentor)
• Committee member: Vedran Cesarec (predsjednik povjerenstva)
• Committee member: Anko Antabak (član povjerenstva)
• Committee member: Tomislav Bečejac (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Surgery

Abstract

Proces dijagnostičke obrade pacijenata s tumorima pluća najčešće započinje identifikacijom kliničkih manifestacija, nakon čega slijedi utvrđivanje etiologije bolesti. Dijagnostički postupci uključuju korištenje slikovnih metoda poput radiograma (RTG), kompjuterizirane tomografije (CT), i pozitronske emisijske tomografije (PET). Potvrda malignosti i određivanje stadija bolesti ključni su za planiranje optimalnog terapijskog pristupa. Minimalno invazivne tehnike biopsije pluća su zlatni standard dijagnostike tumora pluća te omogućavaju precizno određivanje histološkog tipa tumora. Personalizirana terapija, temeljena na molekularnim i genetskim profilima tumora, omogućava ciljani pristup koji značajno poboljšava uspješnost liječenja i kvalitetu života oboljelih.
Kirurško liječenje je osnovni modalitet za lokalizirane tumore pluća i uključuje zahvate poput segmentektomije, lobektomije i pulmektomije. Napredak u minimalno invazivnim tehnikama, poput video-asistirane torakoskopske kirurgije (VATS), doprinosi smanjenju perioperativnih komplikacija, bržem postoperativnom oporavku te poboljšava kvalitetu života pacijenata.

Abstract (english)

The process of diagnostic evaluation of patients with lung tumors usually begins with the identification of clinical manifestations, followed by determination of the etiology of the disease. Diagnostic procedures include the use of imaging methods such as radiography (X-ray), computed tomography (CT) and positron emission tomography (PET). Confirmation of malignancy and staging are crucial for planning the optimal therapeutic approach. Minimally invasive lung biopsy techniques are the gold standard for diagnosing lung tumors, allowing precise determination of the histological type of the tumor. Personalized therapy, based on the molecular and genetic profiles of the tumor, enables a targeted approach that significantly improves the success of the treatment and quality of life of patients.
Surgical treatment is the primary modality for localized lung tumors and includes procedures such as segmentectomy, lobectomy and pneumonectomy. Advances in minimally invasive techniques, such as video-assisted thoracoscopic surgery (VATS), contributes to the reduction of the perioperative complications, faster postoperative recovery and enhances the quality of life for patients.

• Keywords: tumori pluća; biopsija pluća; lobektomija; segmentektomija; VATS
• Keywords (english): lung tumors; lung biopsy; lobectomy; segmentectomy; VATS
• Language: croatian
• URN:NBN: urn:nbn:hr:105:100361
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-06-27 16:10:40