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Termičke promjene tijekom cijeljenja prijeloma distalnoga radijusa
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Damir Halužan Cijeljenje kosti je vrlo kompleksno. Prilikom cijeljenja prijeloma dolazi do povećanja protoka krvi oko mjesta prijeloma, što dovodi do porasta temperature. Infracrvena termografija metoda je mjerenja temperature tijela koja može detektirati termičke promjene.
Provedeno je prospektivno istraživanje na 50 bolesnika s ciljem istraživanja termičkih promjena tijekom cijeljenja prijeloma distalnoga radijusa te na 30 zdravih dobrovoljaca sa svrhom validacije metode. Mjerenje je izvršeno...
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Termičko oštećenje kosti tijekom bušenja dvostupnjevanim svrdlom i svrdlom s protočnim hlađenjem
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Goran Augustin Svrha rada. Bušenje kosti uzrokuje porast temperature, a temperatura iznad kritične od 47oC dovodi do termičke nekroze kosti. Temperature iznad kritične izražene su uporabom svrdla promjera ≥ 4.5 mm bez hlađenja. Cilj istraživanja je ispitati utjecaj različitih parametara, kao i njihovih interakcija, na porast temperature kosti korištenjem novokontruiranih svrdla (dvostupnjevanog svrdla i svrdla sa protočnim hlađenjem).
----- Materijali i metode. Plan pokusa napravljen je...
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Tezaurus MeSH kao okvir za analizu predmetnih odrednica u sadržajnoj obradi hrvatske medicinske literature
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Lea Škorić Organizacija, sustavna pohrana i omogućivanje pristupa informacijama među najvažnijim su zadaćama informacijskih stručnjaka. Predmetni pristup informacijama u ovom je radu istražen na uzorku odabranih hrvatskih znanstvenih časopisa i monografija medicinske tematike.
U uvodnom dijelu rada izložena su teoretska uporišta i različiti sustavi organizacije informacija, s posebnim osvrtom na razvoj, strukturu i važnost tezaurusa te suvremenu problematiku organizacije informacija u...
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Težina koronarne bolesti u akutnom koronarnom sindromu u romskoj populaciji u sjeverozapadnoj Hrvatskoj
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Vanja Hulak-Karlak Istraživanje je provedeno u 5-godišnjem razdoblju i obuhvatilo je sve bolesnike hospitalizirane u KB Dubrava pod dijagnozom akutnog koronarnog sindroma. Gravitacijsko područje KB Dubrava osim dijela grada Zagreba i Zagrebačke županije, obuhvaća i Međimursku, Varaždinsku te Koprivničko-križevačku županiju. Navedeni lokaliteti i županije smatraju se područjima visoke gustoće romskog stanovništva. Bolesnici su temeljem etničke pripadnosti, koja je procjenjena specifičnim...
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The Impact of Pre-Hospital Emergency Care on Outcome in Patients with Acute Coronary Syndrome
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Musli Gashi Emergency medicine, a field relatively new to even the most developed societies, is in its infancy in Kosova. The general aim of the study was to evaluate the impact of pre-hospital and hospital emergency care in the prognosis of patients admitted to the hospital with ACS. This observational prospective clinical study has included all cases of ACS patients admitted to emergency department of UCCK between January 1, 2011 and December 31, 2012. During this period 1498 patients diagnosed as...
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The effect of spinopelvic parameters on the development of proximal junctional kyphosis in early onset scoliosis
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Ozren Kubat Pre- and postoperative spinopelvic anatomy can influence results of distraction treatment in early onset scoliosis. I hypothesize patients with abnormal spinopelvic alignment have increased risk of proximal junctional kyphosis (PJK) during distraction treatment. Patients were treated between April 1997 and August 2014. A subsegment of patients were evaluated for quality of life. 135 patients were treated at an average age of 5.3 ± 2.83 years (range, 0.97-12.18), with minimum 2-year...
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The frequency of micronuclei in peripheral blood lymphocytes and buccal exfoliated cells in women with cervical cancer
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Goneta Gashi Biološki marker predstavlja važan dio u dijagnostici, prognozi i procjeni rizika za određenu bolest. Cilj rada bio je procijeniti genomsku nestabilnost kod pacijentica sa cervikalnim lezijama.
Genetska oštećenja su istraživana kod 100 žena /20 bolesnica sa skvamoznom intraepitelnom lezijom niskog stupnja (LSIL), 40 bolesnica sa skvamoznom intraepitelnom lezijom visokog stupnja (HSIL), 20 bolesnica sa invazivnim rakom vrata maternice (SCC), 20 žena bez bolesti, kao kontrolna skupina/,...
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The impact of apelin level on the incidence of major adverse cardiac events after myocardial infarction with ST elevation
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Xhevdet Krasniqi Background: During acute myocardial infarction, phosphorylated TnI levels, Ca2+ sensitivity and ATPase activity are decreased in the myocardium, and the elevation in Ca2+ levels activates protease I (calpain I), leading to the proteolytic degradation of troponins. Concurrently, hypoxia enhanced the expression of hypoxia inducible factor 1 alpha (HIF-1a) increasing the level of apelin, which limits infarct size, and improves myocardial function. -----
Methods: In this prospective...
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The risk of Lyme borreliosis infection following tick bite in Pristina region, Kosovo
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Albina Ponosheci-Biçaku Aim: No clinical and seroprevalence studies for Lyme borreliosis (LB) in Kosovo have been publicly available thus far. Therefore, we performed a prospective observational study with the primary objective of defining the risk of developing Lyme borreliosis after a tick bite in Kosovo. Materials and methods: A total of 380 adult participants (≥18 years of age) with an embedded tick in the skin examined at the Clinic of Infectious Diseases, Pristina, were included in the study during the four...
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The role of Interleukin-7 serum levels as a biological marker in breast cancer
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Faton Sermaxhaj Background: The aim of this study has been to explore whether there is any difference of Interleukin-7 serum concentration in early invasive breast cancer (EIBC) patients in comparison with healthy controls. In addition, the correlation between the IL-7 serum concentration and histopathological characteristics of the tumor has been evaluated. -----
Methods: This cross-sectional and analytical study has included 213 consecutive patients with EIBC and 62 healthy participants as the control...
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The role of liver sinusoidal endothelial cells in HCV infection
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Neven Papić INTRODUCTION: Liver sinusoidal endothelial cells (LSEC) due to their
extraordinary scavenger activity are playing a pivotal role in blood-borne virus
clearance. LSEC account for the 20% of hepatic cells and are unique organresident
cell population with diverse functions, including degradation of bacterial
by-products, antigen presentation and induction of tolerance. While these
processes are particularly relevant to HCV infection, the role of LSEC in chronic
hepatitis C is not defined. -----...
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