Stres i neplodnost

master's thesis

• Author: Lara Pavlica
• Mentor: Ivan Bolanča (mentor)
• Committee member: Dinka Pavičić Baldani (predsjednik povjerenstva)
• Committee member: Dražen Begić (član povjerenstva)
• Committee member: Ivan Bolanča (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; Zagreb
• Defense date and country: 2024-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Gynecology and Obstetrics

Abstract

Ovaj rad istražuje kompleksan odnos između stresa i ženskog reproduktivnog zdravlja, s posebnim naglaskom na utjecaj stresa na plodnost i uspjeh postupaka medicinski potpomognute oplodnje (MPO). Također analizira kako stres, kao jedan od ključnih čimbenika, može djelovati na reproduktivne funkcije i potencijalno dovesti do neplodnosti. Neplodnost se definira kao nemogućnost postizanja kliničke trudnoće nakon 12 ili više mjeseci redovitih nezaštićenih seksualnih odnosa, a smatra se značajnim medicinskim, psihosocijalnim i ekonomskim problemom. Fokus rada je na ženskoj neplodnosti koja se može podijeliti na primarnu i sekundarnu. Etiologija neplodnosti uključuje niz čimbenika kao što su poremećaji ovulacije, patologija jajovoda i maternice te genetski poremećaji. Posebno se kao uzrok ističe još i sindrom policističnih jajnika (PCOS) koji je najčešći endokrini poremećaj u žena reproduktivne dobi. Stres se također ističe kao jedan od faktora koji mogu utjecati na plodnost tako što ima negativni utjecaj na balans hormona i ovulaciju. Također, neplodnost sama po sebi može biti izvor značajnog stresa, stvarajući začarani krug u kojem stres pogoršava neplodnost, a neplodnost izaziva dodatni stres. Ova recipročnost može imati ozbiljne psihološke i emocionalne posljedice za parove koji pokušavaju zatrudnjeti. Osim toga, naglašava se i utjecaj stresa na ishode postupaka MPO-a, poput in vitro oplodnje (IVF). Istraživanja obrađena u ovom radu pokazuju da visoka razina stresa može smanjiti uspješnost IVF-a, dok smanjenje stresa može poboljšati šanse za uspješni ishod postupka. Zaključno, ovaj rad naglašava važnost sveobuhvatnog pristupa liječenju neplodnosti, koji obuhvaća ne samo medicinske tretmane već i psihološku podršku pacijentima kako bi se smanjio stres i povećale šanse za uspješno iznesenu trudnoću.

Abstract (english)

This paper explores the complex relationship between stress and women's reproductive health, with a particular focus on the impact of stress on fertility and the success of assisted reproductive technology (ART) procedures. It also analyzes how stress, as a key factor, can affect reproductive functions and potentially lead to infertility. Infertility is defined as the inability to achieve a clinical pregnancy after 12 or more months of regular unprotected intercourse and is considered to be a significant medical, psychosocial, and economic issue. This paper focuses on female infertility, which can be divided into primary and secondary types. The etiology of infertility includes a range of factors such as ovulation disorders, fallopian tube and uterine pathology, and genetic disorders. Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of a reproductive age and is also one of the primary causes for female infertility. Stress is also emphasized as a factor that can affect fertility by negatively impacting hormonal balance and ovulation. Furthermore, infertility itself can be a significant source of stress, creating a vicious cycle where stress worsens infertility, and infertility causes additional stress. This reciprocity can have serious psychological and emotional consequences for couples trying to conceive. Additionally, the impact of stress on the outcomes of ART procedures, such as in vitro fertilization (IVF) is also highlighted. The research reviewed in this paper shows that high levels of stress can reduce the success of IVF, while reducing stress may improve the chances of a successful outcome. In conclusion, this paper highlights the importance of a comprehensive approach to treating infertility, which includes not only medical treatments but also psychological support to reduce stress and increase the likelihood of a successful pregnancy.

• Keywords: neplodnost; stres; ovulacija; medicinski potpomognuta oplodnja; in vitro oplodnja
• Keywords (english): infertility; stress; ovulation; assisted reproductive technology; in vitro fertilization
• Language: croatian
• URN:NBN: urn:nbn:hr:105:764986
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-09-02 11:24:06