Novosti u endohepatologiji

master's thesis

• Title (english): Updates in endohepatology
• Author: Duje Škaričić
• Mentor: Tajana Pavić (mentor)
• Committee member: Neven Baršić (predsjednik povjerenstva)
• Committee member: Marija Bakula (član povjerenstva)
• Committee member: Tajana Pavić (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Internal Medicine); Zagreb
• Defense date and country: 2024-09-11, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Internal Medicine

Abstract

Endohepatologija je relativno nova grana u hepatologiji koja kombinira ultrazvučne i endoskopske modalitete kako bi se poboljšala dijagnostika i liječenje različitih bolesti jetre. Omogućuje liječnicima korištenje minimalno invazivnih pristupa koji pružaju veću preciznost u usporedbi s tradicionalnim metodama. Posebno se ističe integracija endoskopskog ultrazvuka (EUS), koja je značajno proširila mogućnosti dijagnosticiranja i liječenja jetrenih patologija.
Kliničke primjene EUS-a kod jetrene patologije, uključujući portalnu hipertenziju, jetrene tumore i kronične jetrene bolesti, naglašavaju njegovu važnu ulogu u osiguravanju preciznijih procjena i omogućavanju ciljanih terapijskih intervencija. Ovaj pristup može značajno poboljšati ishode liječenja smanjenjem potrebe za invazivnim zahvatima, čime se smanjuju rizici za pacijente i ubrzava njihov oporavak. EUS nudi mogućnost kombiniranja dijagnostike i terapije u jednom postupku, što dodatno povećava njegovu učinkovitost i korisnost u kliničkoj praksi.
Unatoč značajnim naprecima u ovom području, i dalje postoje izazovi koji ograničavaju širu primjenu ovih tehnika. Među glavnim izazovima su visoki troškovi potrebne opreme, potreba za specijaliziranom obukom medicinskog osoblja, te ograničena dostupnost opreme u manje razvijenim zdravstvenim ustanovama. Međutim, endohepatologija će imati sve važniju ulogu u kliničkoj praksi, pogotovo u složenim slučajevima jetrenih bolesti gdje konvencionalni pristupi nisu jednako učinkoviti.

Abstract (english)

Endohepatology is a relatively new branch of hepatology that combines ultrasound and endoscopic modalities to enhance the diagnosis and treatment of various liver diseases. It allows physicians to utilize minimally invasive techniques that offer greater precision compared to traditional methods. The integration of endoscopic ultrasound (EUS) is particularly notable, as it has significantly expanded the possibilities for diagnosing and treating liver pathologies.
The clinical applications of EUS in liver diseases, including portal hypertension, liver tumours, and chronic liver diseases, underscore its important role in providing more accurate assessments and enabling targeted therapeutic interventions. This approach can significantly improve treatment outcomes by reducing the need for invasive procedures, thus lowering risks for patients and accelerating their recovery. EUS also offers the advantage of combining diagnosis and therapy in a single procedure, further enhancing its effectiveness and utility in clinical practice.
Although significant progress has been made, there are still remaining challenges that limit the wider acceptance. Among the main challenges are the high costs of the necessary equipment, the need for specialized training of medical staff, and the limited availability of equipment in less developed healthcare institutions. However, endohepatology is expected to play an increasingly important role in clinical practice, especially in complex cases of liver diseases where conventional approaches aren't sufficiently effective.

• Keywords: endoskopija; endosonografija; ezofagealni i gastrični varikoziteti; jetrene bolesti; portalna hipertenzija
• Keywords (english): endoscopy; endosonography; esophageal and gastric varices; liver diseases; portal hypertension
• Language: croatian
• URN:NBN: urn:nbn:hr:105:457687
• Study programme: Title: Medicine; Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-09-06 15:29:11