Postoperative Nausea and Vomiting

master's thesis

• Title (english): Postoperativna mučnina i povraćanje
• Author: Amanda Lynn LaBar
• Mentor: Vilena Vrbanović Mijatović (mentor)
• Committee member: Vilena Vrbanović Mijatović (predsjednik povjerenstva)
• Committee member: Daniela Bandić Pavlović (član povjerenstva)
• Committee member: Dinko Tonković (član povjerenstva)
• Granter: University of Zagreb; School of Medicine; (Department of Anaesthesiology, Resuscitation and Intensive Care in Surgical Specialities); Zagreb
• Defense date and country: 2024-07-12, Croatia
• Scientific / art field, discipline and subdiscipline: BIOMEDICINE AND HEALTHCARE; Clinical Medical Sciences; Anesthesiology and Reanimatology

Abstract

A comprehensive review of postoperative nausea and Vomiting (PONV) is presented, a widely recognized side effect occurring within the first 24 hours following a surgical procedure. This review aims to identify the factors influencing PONV, including patient-specific traits, anesthetic methods, and surgical interventions. It explains the neural pathways controlling vomiting and evaluates pharmacological and non-pharmacological approaches to managing PONV. Additionally, this thesis highlights the consequences associated with PONV and the importance of preventive measures tailored to individual risk profiles. It explores various methods in PONV management, including genetic investigations and nerve stimulation techniques, to improve patient outcomes and satisfaction. It emphasizes the complex nature of PONV, the significance of understanding contributing factors such as patient characteristics, anesthetic techniques, and surgical procedures, and the roles of pharmacological and non-pharmacological interventions in managing PONV.

Abstract (croatian)

Prikazan je opsežan pregled postoperativne mučnine i povraćanja (PONV), široko poznate nuspojave koja se javlja unutar prva 24 sata nakon kirurškog zahvata. Ovaj pregled ima za cilj identificirati čimbenike koji utječu na PONV, uključujući osobine specifične za pacijenta, metode anestezije i kirurške intervencije. Objašnjava neuralne putove koji kontroliraju povraćanje i
procjenjuje farmakološke i nefarmakološke pristupe liječenju PONV-a. Dodatno, u radu se naglašavaju posljedice povezane s PONV-om i važnost preventivnih mjera prilagođenih individualnim profilima rizika. Istražuje različite metode zbrinjavanja PONV-a, uključujući genetske pretrage i tehnike stimulacije živaca, kako bi se poboljšali ishodi i zadovoljstvo pacijenata. Naglašava složenu prirodu PONV-a, važnost razumijevanja čimbenika koji doprinose kao što su karakteristike bolesnika, tehnike anestezije i kirurški postupci te ulogu farmakoloških i nefarmakoloških intervencija u liječenju PONV-a.

• Keywords: Postoperative nausea and Vomiting; PONV; surgery; anesthesia; risk factors; vomiting center; APFEL score
• Keywords (croatian): Postoperativna mučnina i povraćanje; PONV; operacija; anestezija; faktori rizika; centar za povraćanje; APFEL rezultat
• Language: english
• URN:NBN: urn:nbn:hr:105:048161
• Study programme: Title: Medicine (in English language); Study programme type: university; Study level: integrated undergraduate and graduate; Academic / professional title: doktor/doktorica medicine (doktor/doktorica medicine)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2024-10-18 09:25:55